Electron Microscopy at Scale

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Electron Microscopy at Scale Linnaea Ostroff, Hongkui Zeng Cell Volume 162, Issue 3, Pages 474-475 (July 2015) DOI: 10.1016/j.cell.2015.07.031 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Neurons Are Selective in Their Choice of Partners The intricate and often surprising interactions between cells in brain tissue can be revealed by dense reconstruction from electron micrographs, as Kasthuri et al. demonstrate on a large scale in this issue. (A) Electron micrograph of adult rat brain showing an axon (blue) forming separate synapses with two dendritic spine heads (asterisks). Volume reconstruction from serial sections reveals that the postsynaptic elements are two separate spines from the same parent dendrite (red). (B) Three dimensional rendering of the dendrite (red) and axon (blue) in (A). Scale bar, 500 nm. (Images provided by L.O.) Cell 2015 162, 474-475DOI: (10.1016/j.cell.2015.07.031) Copyright © 2015 Elsevier Inc. Terms and Conditions