David M. Lemchak, DO, Oleg E. Akilov, MD, PhD

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Presentation transcript:

Interleukin-12 immunohistochemistry as a diagnostic tool for patch-stage mycosis fungoides David M. Lemchak, DO, Oleg E. Akilov, MD, PhD Journal of the American Academy of Dermatology Volume 75, Issue 5, Pages 1053-1054 (November 2016) DOI: 10.1016/j.jaad.2016.06.019 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 IL-12p35 staining in mycosis fungoides (MF), psoriasis, and nummular eczema. A, Extracellular and intracellular localization of IL-12p35 of dendritic cells in patch stage mycosis fungoides. (Original magnification: ×20; insert ×100.) B, IL-12p35 demonstrates sporadic staining of Langerhans cells in psoriatic skin. (Original magnification: ×20.) C, Negative IL-12p35 staining in the nummular eczema. (Original magnification: ×20; insert ×100.) D, Immunohistochemistry (IHC) score: 5 patients with patch MF, 5 patients with psoriasis vulgaris, and 5 patients with nummular eczema. *P < .05; **P < .01. Journal of the American Academy of Dermatology 2016 75, 1053-1054DOI: (10.1016/j.jaad.2016.06.019) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions