Trophectoderm grade predicts outcomes of single-blastocyst transfers

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Trophectoderm grade predicts outcomes of single-blastocyst transfers Micah J. Hill, D.O., Kevin S. Richter, Ph.D., Ryan J. Heitmann, D.O., James R. Graham, M.S., Michael J. Tucker, Ph.D., Alan H. DeCherney, M.D., Paulette E. Browne, M.D., Eric D. Levens, M.D. Fertility and Sterility Volume 99, Issue 5, Pages 1283-1289.e1 (April 2013) DOI: 10.1016/j.fertnstert.2012.12.003 Copyright © 2013 Terms and Conditions

Figure 1 Examples of blastocyst grading. (A) early blastocyst BB; (B) early blastocyst AA; (C) expanded blastocyst AA; (D) expanded blastocyst BA; (E) expanded blastocyst AB; (F) expanded blastocyst CC; (G) expanded blastocyst AC; (H) hatching blastocyst BA; (I) expanded blastocyst AA. Fertility and Sterility 2013 99, 1283-1289.e1DOI: (10.1016/j.fertnstert.2012.12.003) Copyright © 2013 Terms and Conditions

Figure 2 Graphic comparison of miscarriage rates based on each morphologic grade. (A) Comparison based on embryo expansion. (B) Comparison based on inner cell mass (ICM) and trophectoderm (TE) grades. Grade C not shown, because there were no miscarriages owing to very low numbers in both of these groups. a,b Statistically significant (P<.05) difference between a and b. Fertility and Sterility 2013 99, 1283-1289.e1DOI: (10.1016/j.fertnstert.2012.12.003) Copyright © 2013 Terms and Conditions

Supplemental Figure 1 Live birth rates for day 5 (top) and day 6 (bottom) blastocyst transfers based on trophectoderm (TE) and inner cell mass (ICM) grading. The number of patients in each category is displayed below the chart. a,b Comparisons between a and b by chi-square analysis: P<.001. Fertility and Sterility 2013 99, 1283-1289.e1DOI: (10.1016/j.fertnstert.2012.12.003) Copyright © 2013 Terms and Conditions