Copyright @2007 ClinTrialStat Inc. All rights reserved Software for Making Mock Tables, Metadata Document, SAS Table Programs of Statistical Analysis Plan, and eCRF pages of EDC System ClinTrialStat Inc. Copyright @2007 ClinTrialStat Inc. All rights reserved

Application Software Developed by ClinTrialStat SapMaker products for making text contents, mock tables and figures, metadata documents, and table SAS code of Statistical Analysis Plan (SAP): SapMaker-Table 3.4 – for mock tables/figures and SAS code SapMaker-Content 2.0 – for text contents SapMaker-Metadata 2.4 – for metadata document eCRF – Builder 1.0: making internet/intranet based electronic case report form (eCRF) of electronic data capture (EDC) system

SapMaker-Content: Easily make individual SAP sections

SapMaker-Content: using search engine feature to quickly find related information from other document

SapMaker-Table: Quickly making individual mock tables and figures of SAP

Machine automatically created mock table

SAS Coder: Easily making table SAS code

SAS Coder: Easily making table SAS code

Easily making mock figure

Machine created mock figure

SapMaker-Metadata: Quickly making metadata document for analysis datasets following CDISC standards

Machine created metadata document following CDISC standards (in Excel file)

Machine converted metadata document to Define.xml for e-Submission

eCRF Builder: Quickly making Internet/Intranet based eCRFs

Machine created eCRF page

Machine created the eCRF page corresponded CDISC ODM Define.xml file

Created machine readable ODM Define.xml file for e-submission

SapMaker special language feature: Making table in Chinese

Created mock table in Chinese

Use SAS Coder created real table in Chinese

Service of ClinTrialStat Help clients customize the SapMaker software products, such as modifying the templates of mock tables of SAP, and SAS macros for creating analysis tables, to meet the specified needs or the standards of the clients; Help clients customize the eCRF-Builder software product, such as modifying the templates of eCRF pages, to meet the specified standards of the clients for CRFs; Make eCRF pages for clients; Make SAP, metadata, and/or SAS table codes for clients

Users of ClinTrialStat Software Products Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115 Vertex Pharmaceuticals, Inc., Cambridge MA 02139 Millennium Pharmaceuticals, Inc. Cambridge, MA 02139 Novo Nordisk Inc., Princeton, New Jersey d.s.h. statistical services GmbH, Rohrbach, Germany US Army Medical Research and Materiel Command, Ft. Detrick, MD 21702-5012 University Eye Center, Duke University, Durham, NC 27710 Department of Medical Biostatistics, University of Vermont, Burlington, VT 05405 Department of Biostatistics, University of South Florida, Tempa, FL Ockham Development Group, Inc., Cary, NC 27511

License Price of SapMaker Software Products SapMaker-Table 3.4 – $698 for per PC install * SapMaker-Content 2.0 – $98 for per PC install SapMaker-Metadata 2.4 – $498 for per PC install For academic users, there is a 25% discount on price of license. * Not include SAS macros

About Us: Mission: ClinTrialStat provides statistical data analysis of clinical trials through application solution products and professional services. It is our mission to provide services and products of excellent quality that offer cost-effective solutions. Products: SapMaker-Content 2.0, SapMaker-table 3.4, Sapmaker-Metadata 2.3, and eCRF- Builder 1.0 Services: Customize SapMaker software products to implement standards of customers, develop SAP, Programming SAS tables, and eCRF web pages Company Information: ClinTrialStat Inc Belle Mead, New Jersey 08502, USA Phone: 908-938-8330, Fax: 908-359-3583 Email: clintrialstat@yahoo.com, Web: http://www.sapmaker.com  Asian Branch Office: ClinTrialStat China, Ltd. 125 East Ming Road, New Technique Development Zorn, Kunming, Yunnan, China