Fig. 1 Finite element model and calculations.

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Fig. 1 Finite element model and calculations. Finite element model and calculations. (A) Three-dimensional (3D) finite element (FE) model of the 4-cm tibia defect in sheep stabilized with a locking compression plate (LCP) and augmented with a Ti-mesh scaffold. (B) 3D FE model of the 4-cm bone defect in sheep stabilized with a custom-made shielding plate (half-shell steel plate) and augmented with a Ti-mesh scaffold. (C) Honeycomb scaffolds formed by titanium struts of the same length (7 mm) but different diameters (1.2 and 1.6 mm). Scaffolds consist of a cylinder (2 cm in diameter and 4 cm in length) and a hole that follows the medullary canal (1 cm in diameter). Top: Von Mises stresses in soft and stiff scaffolds stabilized with an LCP. Bottom: Von Mises stresses in soft and stiff scaffolds stabilized with a custom-made shielding plate. (D) Top: Absolute maximum (Abs. max.) principal strains within the soft and stiff scaffolds stabilized with an LCP. Bottom: Abs. max. principal strains within the soft and stiff scaffolds stabilized with a custom-made shielding plate. Anne-Marie Pobloth et al., Sci Transl Med 2018;10:eaam8828 Published by AAAS