About Me Matt Danzi Research Mentors – Vance Lemmon and John Bixby

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Presentation transcript:

About Me Matt Danzi Research Mentors – Vance Lemmon and John Bixby Third year Ph.D. candidate B.S. from UNC Chapel Hill in Biology with minors in Computer Science and Chemistry Research Mentors – Vance Lemmon and John Bixby Departments: Miami Project to Cure Paralysis and Department of Neurological Surgery Research interest: axon regeneration Computational Mentor – Stefan Wuchty Department of Computer Science Research interest: biological network modelling and prediction

Identifying the Regulators in RNA-Seq Data 46,078 Genes Log2(Fold Change) of Gene Expression 4 2 -2 -4 95 Transcription Factors Yellow = gene regulated by transcription factor Blue = gene not regulated by transcription factor

What I hope to accomplish by April Written and debugged the two planned approaches Applied these two approaches to four data sets Ideally, see a large degree of similarity between the results from each of the four data sets