Salivary Gland Involvement in Chronic Graft-Versus-Host Disease: Prevalence, Clinical Significance, and Recommendations for Evaluation Matin M. Imanguli, Jane C. Atkinson, Sandra A. Mitchell, Daniele N. Avila, Rachel J. Bishop, Edward W. Cowen, Manuel B. Datiles, Frances T. Hakim, David E. Kleiner, Michael C. Krumlauf, Steven Z. Pavletic Biology of Blood and Marrow Transplantation Volume 16, Issue 10, Pages 1362-1369 (October 2010) DOI: 10.1016/j.bbmt.2010.03.023 Copyright © 2010 Terms and Conditions
Figure 1 (A) Photomicrograph of a salivary gland showing SS-like periductal inflammation, with a periductal infiltrate composed predominantly of lymphocytes. (Hematoxylin and eosin; original magnification 200×.) (B) Severe atrophy with interstitial fibrosis. Most of the mucinous acinar parenchyma has been lost from this lobule, replaced by ductular metaplasia and increased perilobular adipose tissue. There is a mild, predominant lymphocytic infiltrate in the fibrous interstitium. (Hematoxylin and eosin; original magnification 200×.) Biology of Blood and Marrow Transplantation 2010 16, 1362-1369DOI: (10.1016/j.bbmt.2010.03.023) Copyright © 2010 Terms and Conditions