Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass grafting Carlos A Estrada, MD,

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Presentation transcript:

Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass grafting Carlos A Estrada, MD, MS, James A Young, MD, L Wiley Nifong, MD, W.Randolph Chitwood, MD The Annals of Thoracic Surgery Volume 75, Issue 5, Pages 1392-1399 (May 2003) DOI: 10.1016/S0003-4975(02)04997-4 Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Unadjusted mortality, infections, and resource utilization for patients with and without diabetes mellitus (DM) according to perioperative blood glucose (mean of all tests performed on the day of and the day after surgery). Infections indicate any of the following: sternal wound infections, infection at harvest site, pneumonia, or urinary tract infection. Error bars represent 95% confidence intervals. The Annals of Thoracic Surgery 2003 75, 1392-1399DOI: (10.1016/S0003-4975(02)04997-4) Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Odds ratios for mortality and infections. Adjusted for diabetes status and mortality or mediastinitis risk score, note the increased odds per each 50 mg/dL glucose increase in mortality (1.37, p = 0.07) and infections (1.23, p = 0.14). Infections indicate sternal wound infection, infection at the harvest site, sepsis, pneumonia, or urinary tract infection. The horizontal lines of the odds ratios indicate the 95% confidence intervals (CI). To convert the blood glucose value in milligrams per deciliter to millimoles per liter, divide the value by 18 (50 mg/dL = 2.78 mmol/L). The Annals of Thoracic Surgery 2003 75, 1392-1399DOI: (10.1016/S0003-4975(02)04997-4) Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Beta coefficients for resource utilization. Adjusted for diabetes status and mortality risk score, note the increased value per each 50 mg/dL glucose increase in postoperative days (0.76 days, p < 0.001), hospitalization charges ($2,824, p < 0.001), and hospitalization costs ($1,769, p < 0.001). The horizontal lines of the beta coefficients indicate the 95% confidence intervals (CI). To convert the blood glucose value in milligrams per deciliter to millimoles per liter, divide the value by 18 (50 mg/dL = 2.78 mmol/L). The Annals of Thoracic Surgery 2003 75, 1392-1399DOI: (10.1016/S0003-4975(02)04997-4) Copyright © 2003 The Society of Thoracic Surgeons Terms and Conditions