Journal of Antibiotics

Slides:



Advertisements
Similar presentations
Multipulse techniques
Advertisements

Experiment: Extraction of Vitamins A & C Objective: The objective of this experiment is separate vitamins A and C through an extraction and to confirm.
2DNMR. Coupling Constants Geminal Coupling are usually negative: CH 2 Vicinal coupling usually positive: CH-CH Why? Coupling is through bonding electrons;
Basic Two Dimensional NMR Spectroscopy
J. Nat. Prod. 2004, 67, Steroids and Sesquiterpenoids from the Soft Corals Dendronephthya gigantea and Lemnalia cervicorni Chang-Yih Duh, Ali.
Assign. Shift(ppm) A 7.40 to 7.19 B C 2.3 benzyl alcohol 1H-NMR 90MHz In CDCl3 Low concentration NMR database / spectra etc.:
The molecular formula is C 5 H 8. What is the structure?
4 aromatic protons Can we use 2D to assign this spectrum? Structure first determined by Woodward in 1948 (without NMR!)
Instructions about how to transer a NMR spectrum recorded with The 60MHz, Jeol, JNM-MY60 spectrometer to IGOR, -for further manipulation of the data and/or.
J Nat. Prod. 2006, 69, Cytotoxic Xenia Diterpenoids from the Soft Coral Xenia umbellata Ali A. El-Gamal, Shang-Kwei Wang and Chang-Yih Duh Department.
NMR Applications in Chemistry
Supplemental Information
How to Analyze of 2D NMR Spectra ( small molecules) 노 정 래.
INSTITUTE OF CHEMISTRY DEPARTMENT OF STRUCTURE AND FUNCTION OF SACCHARIDES.
Article Title: AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies Journal.
Ali A. El-Gamal, Shang-Kwei Wang and Chang-Yih Duh Department of Marine Biotechnology and Resources, National Sun Yat-sen University; Kaohsiung, Taiwan.
Antibacterial compounds from the stem barks of Garcinia cowa Ittipon Siridechakorn PhD. Program in Applied Chemistry School of Science, Mae Fah Luang University.
International Conference and Exhibition on Biopolymers and Bioplastics
13. Structure Determination: Nuclear Magnetic Resonance Spectroscopy
Structural Elucidation of a Diterpene Derivative from Stemodia Maritima Eugene E. Kwan and William F. Reynolds April 2003.
Assignments of Hydrogen and Carbon Atoms of Artemisinin
Supplemental Information for: METABOLISM OF RAMELTEON IN HUMAN LIVER MICROSOMES AND CORRELATION WITH THE EFFECT OF FLUVOXAMINE ON RAMELTEON PHARMACOKINETICS.
J. Nat. Prod. 2004, 67, New Nardosinanes and 19-Oxygenated Ergosterols from the Soft Coral Nephthea armata Collected in Taiwan Ali A. H. El-Gamal,
Nuclear Magnetic Resonance
Source Page US:official&tbm=isch&tbnid=Mli6kxZ3HfiCRM:&imgrefurl=
On page 2: Saturation curves for determination of PsAMADH1 and 2 activities with variable concentrations of NAD + in the presence of 1 mmol l -1 aldehyde.
Comanthus parvicirrus ( 小卷海齒花 ) 動物界 (Animalia) 棘皮動物門 (Echinodermata) 海百合綱 (Crinoidea) 關節亞鋼 (Articulata) 海羊齒目 (Comatulida) 櫛羽星科 (Comasteridae) 為一種始見於石炭紀的棘皮動物,生活於海裡,
Путешествуй со мной и узнаешь, где я сегодня побывал.
Figure Molecular Biology of the Cell (© Garland Science 2008)
NF-κB-Inhibiting Naphthopyrones from the Fijian Echinoderm Comanthus parvicirrus Florence Folmer, † William T. A. Harrison, † Jioji N. Tabudravu, † Marcel.
A. S. Edison University of Georgia 2016 Fast Course in NMR Lecture 9 Jan/Feb, 2016 Big picture 1D Review of how we do it Why 2D? What information does.
Discovery of A Novel Source of Chloramphenicol Production by Endophytic Streptomyces SUK 25 sp., Isolated from Zingiber spectabile Against Methicillin.
2D NMR.
Calcium-Induced Conformational Switching of Paramecium Calmodulin Provides Evidence for Domain Coupling Jaren et al. Biochemistry 2002, 41,
A modified Raman multidimensional spectroscopic signature of blood to account for the effect of laser power  Gregory McLaughlin, Igor K. Lednev  Forensic.
Subtitle And Presenter(s)
Supporting Information
Bibliometric Analysis of Herbal Medicine Publications, 1991 to 2004
Rapid Sample Identification Through NMR
INSTITUTE OF CHEMISTRY
Department of Science, systems and Models
Bibliometric Analysis of Water Research
Supporting Information for
What is your FICO IQ Quiz? Link to article attached.
Anti-inflammatory and immunomodulatory effects of ginsenosides from Korea red ginseng April 26 th, 2018 Presenter : Le Ba Vinh, Ph.D student Superviser.
Page 1. Page 2 Page 3 Page 4 Page 5 Page 6 Page 7.
Volume 102, Issue 2, Pages L8-L10 (January 2012)
Nuclear Magnetic Resonance
Supplementary Material
Elucidating Structures
NMR Evidence for Forming Highly Populated Helical Conformations in the Partially Folded hNck2 SH3 Domain  Jingxian Liu, Jianxing Song  Biophysical Journal 
SAMPLE SUBMISSION FORM
Subtitle And Presenter(s)
Subtitle And Presenter(s)
Subtitle And Presenter(s)
SAMPLE SUBMISSION FORM
Solving Unknown Structures Using NMR
Making Sense of Intrinsically Disordered Proteins
Week 13 Analyse absorptions in an infrared spectrum to identify the presence of functional groups in an organic compound. Analyse molecular ion peaks and.
1H, 13C NMR, IR and MS Spectral data for Benzoin
ENQUIRY Q2: 4A.4 Economic and social inequalities changes people’s perceptions of an area.
Subtitle And Presenter(s)
Unusual conformational control of mobile mono- and diionizable
Introduction to NMR Spectroscopy
Introduction to NMR Spectroscopy
Volume 112, Issue 8, Pages (April 2017)
The Usefulness of NMR Quantum Computing
Volume 76, Issue 1, Pages (January 1999)
Introduction to NMR Spectroscopy
Presentation transcript:

Journal of Antibiotics Supplementary information Journal of Antibiotics Original article   Structure elucidation of meroterpenoid habiterpenol, a novel abrogator of bleomycin-induced G2 arrest in Jurkat cells, produced by Phytohabitans suffuscus 3787_5 Ryuji Uchida, Sayaka Yokota, and Hiroshi Tomoda* Graduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan Various NMR spectra were obtained using an Agilent Technologies XL-400 (400 MHz) spectrometer (Agilent Technologies, Santa Clara, CA, USA). Page 1H NMR spectrum of 1 in CDCl3 (600 MHz) 2 13C NMR spectrum of 1 in CDCl3 (150MHz) 3 1H-1H COSY spectrum of 1 in CDCl3 (600 MHz) 4 HSQC spectrum of 1 in CDCl3 (600 MHz) 5 HMBC spectrum of 1 in CDCl3 (600 MHz) 6 ROESYspectrum of 1 in CDCl3 (600 MHz) 7 1

1H NMR spectrum of 1 (in CDCl3, 600 MHz) 2

13C NMR spectrum of 1 (in CDCl3, 150 MHz)

1H-1H COSY spectrum of 1 (in CDCl3, 600 MHz) 4 1H-1H COSY spectrum of 1 (in CDCl3, 600 MHz)

HSQC spectrum of 1 (in CDCl3, 600 MHz) 5

HMBC spectrum of 1 (in CDCl3, 600 MHz)

ROESY spectrum of 1 (in CDCl3, 600 MHz) 7