Lack of TERT promoter mutations in melanomas with extensive regression

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Lack of TERT promoter mutations in melanomas with extensive regression Blanca de Unamuno Bustos, MD, Rosa Murria Estal, MSc, Gema Pérez Simó, BSc, Vicente Oliver Martínez, MD, PhD, Margarita Llavador Ros, MD, Sarai Palanca Suela, PhD, Rafael Botella Estrada, MD, PhD Journal of the American Academy of Dermatology Volume 74, Issue 3, Pages 570-572 (March 2016) DOI: 10.1016/j.jaad.2015.10.003 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Association of TERT promoter mutation status and clinicopathologic features. TERT promoter mutations are associated with sex, location, histological subtype, Breslow thickness, ulceration, regression, and mitosis. P values were derived from χ2-test and considered statistically significant if <.05. Journal of the American Academy of Dermatology 2016 74, 570-572DOI: (10.1016/j.jaad.2015.10.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Distribution of TERT promoter mutations according to regression. TERT promoter mutations were significantly associated with melanomas without regression. None of the melanomas with extensive regression harbored recurrent mutations. Journal of the American Academy of Dermatology 2016 74, 570-572DOI: (10.1016/j.jaad.2015.10.003) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions