Case 1. Case 1. (A) Low power photomicrograph of renal medulla showing a poorly formed granuloma with several disrupted and destroyed renal tubules within.

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Case 1. Case 1. (A) Low power photomicrograph of renal medulla showing a poorly formed granuloma with several disrupted and destroyed renal tubules within the centre of the granuloma. (B, C) Higher power photomicrographs showing the histiocytes forming a granuloma intimately associated with the disrupted and destroyed renal tubules. (D) Low power photomicrograph showing renal cortical tubules elsewhere within the same biopsy, which appeared unremarkable. A mild interstitial lymphocytic nephritis is present. A Mahmood et al. J Clin Pathol 2004;57:551-552 Copyright © by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.