Rémy Denzler, Markus Stoffel Molecular Cell

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The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis Rémy Denzler, Markus Stoffel Molecular Cell Volume 60, Issue 1, Pages 4-6 (October 2015) DOI: 10.1016/j.molcel.2015.09.014 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 pri-miRNA Structure Influences Its Processing Efficiency (A) Schematic illustration of pri-miRNA biogenesis depicting the sequence determinants in mammalian pri-miRNA, and its orientation in relation to components of the Microprocessor complex. (B) Summary of how the sequence and structure determinants of mammalian pri-miRNA influence processing efficiency in pri-miRNA that have different stem-loop lengths and contain unstructured features (mismatches and bulges in the stem). Molecular Cell 2015 60, 4-6DOI: (10.1016/j.molcel.2015.09.014) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 Impact of pri-miRNA Features for Technical Applications and Biological Insights Molecular Cell 2015 60, 4-6DOI: (10.1016/j.molcel.2015.09.014) Copyright © 2015 Elsevier Inc. Terms and Conditions