Plasma thrombin-antithrombin complex, prothrombin fragments 1 and 2, and D-dimer levels are elevated after endovascular but not open repair of infrarenal.

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Plasma thrombin-antithrombin complex, prothrombin fragments 1 and 2, and D-dimer levels are elevated after endovascular but not open repair of infrarenal abdominal aortic aneurysm  Marc A. Bailey, MB, ChB, BSc, MRCS, Kathryn J. Griffin, MB, Bchir, MA, MRCS, Soroush Sohrabi, PhD, MRCS, Daniel J. Whalley, BSc, MRes, Anne B. Johnson, RN, Paul D. Baxter, PhD, CStat, Robert A.S. Ariëns, BSc, PhD, D. Julian A. Scott, MD, FRCS, FRCS(Ed), FEBVS  Journal of Vascular Surgery  Volume 57, Issue 6, Pages 1512-1518 (June 2013) DOI: 10.1016/j.jvs.2012.12.030 Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig Differences in markers of coagulation activation before and after intervention are shown in patients with abdominal aortic aneurysms (AAAs). Box-and-whisker plots demonstrate the differences in (A) thrombin-antithrombin complex (TAT), (B) prothrombin fragments 1 and 2 (F1+2), and (C) D-dimer before and after open aneurysm repair (OAR; red) and endovascular aneurysm repair (EVAR; blue). *P < .01 on multiple linear regression modelling controlling for glycosylated hemoglobin A1c and age. The horizontal line in the middle of each box indicates the median; the top and bottom borders of the box mark the 75th and 25th percentiles, respectively, and the whiskers mark the 90th and 10th percentiles. TAT, prothrombin fragments 1 and 2, and D-dimer levels are elevated after endovascular but not open repair of infrarenal AAAs. Journal of Vascular Surgery 2013 57, 1512-1518DOI: (10.1016/j.jvs.2012.12.030) Copyright © 2013 Society for Vascular Surgery Terms and Conditions