Volume 131, Issue 3, Pages 719-728 (September 2006) Cost Analysis and Cost Determinants in a European Inflammatory Bowel Disease Inception Cohort With 10 Years of Follow-up Evaluation  Selwyn Odes, Hillel Vardi, Michael Friger, Frank Wolters, Maurice G. Russel, Lene Riis, Pia Munkholm, Patrizia Politi, Epameinondas Tsianos, Juan Clofent, Severine Vermeire, Estela Monteiro, Iannis Mouzas, Giovanni Fornaciari, Jildou Sijbrandij, Charles Limonard, Gilbert Van Zeijl, Colm O’Morain, Bjørn Moum, Morten Vatn, Reinhold Stockbrugger  Gastroenterology  Volume 131, Issue 3, Pages 719-728 (September 2006) DOI: 10.1053/j.gastro.2006.05.052 Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 1 The mean annual expenditure on inflammatory bowel disease for total health care, hospitalization, diagnostics, and medication, and the median annual expenditure for total health care in the EC-IBD cohort with 10 years of follow-up evaluation. Data are arranged so that year 1 is the inception year of each patient. The median cost of total health care was equal to about one third of the mean, confirming the right skew of the mean cost data. ▴, total, mean; ■, total, median; ■, mean hospitalization; -▴-, mean medication; •, mean diagnostics. Gastroenterology 2006 131, 719-728DOI: (10.1053/j.gastro.2006.05.052) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 2 The proportional expenditure on resources used by the EC-IBD countries in the care of inflammatory bowel disease patients. The total expenditure per country is given as 100%, which is divided per resource category. Surgical hospitalization includes the cost of surgery. ■, Medical hospitalization; , surgical hospitalization; □, diagnostics; , mesalamines; , other drugs (steroids, antibiotics, immunomodulators, infliximab, and others). Gastroenterology 2006 131, 719-728DOI: (10.1053/j.gastro.2006.05.052) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 3 The mean annual hospitalization rates in the EC-IBD cohort with 10 years of follow-up evaluation. (A) Total hospitalization rates (medical and surgical) of Crohn’s disease and ulcerative colitis. , Ulcerative colitis; □, Crohn’s disease. (B) Medical and surgical hospitalization rates of inflammatory bowel disease. , Medical hospitalization; □, surgical hospitalization. Gastroenterology 2006 131, 719-728DOI: (10.1053/j.gastro.2006.05.052) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions