Widespread Immunological Functions of Mast Cells: Fact or Fiction?

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Widespread Immunological Functions of Mast Cells: Fact or Fiction? Hans-Reimer Rodewald, Thorsten B. Feyerabend Immunity Volume 37, Issue 1, Pages 13-24 (July 2012) DOI: 10.1016/j.immuni.2012.07.007 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 Diversity and Experimental Basis of Assumed Functions of Mast Cell in the Immune System and Beyond Mast cell functions are classified into “protective,” “harmful,” and “ill-defined.” The latter category comprises studies that were based on analyses of Kit mutants only, that gave conflicting data in different Kit mutants, or that have not been confirmed when tested in Kit-independent models. These categories are further structured for immunological functions, e.g., innate and adaptive immunity, allergy, or autoimmunity, and for diseases, e.g., infections, anaphylaxis, or arthritis. The experimental bases of the mast cell analyses are discussed and referenced in the text. Immunity 2012 37, 13-24DOI: (10.1016/j.immuni.2012.07.007) Copyright © 2012 Elsevier Inc. Terms and Conditions