Figure 1 Clinical correlates of neurodegeneration in MS

Slides:

Advertisements

Similar presentations

Table 3 Limb-girdle muscular dystrophy standardized data collection form and HPO mapping Thompson, R. & Straub, V. et al. (2016) Limb-girdle muscular dystrophies.

Advertisements

Nat. Rev. Neurol. doi:10/1038/nrneurol

Nat. Rev. Neurol. doi: /nrneurol

Figure 2 Electromechanical properties of OIHPs

Figure 6 Selected examples of TERS applications in material systems

Figure 3 Life expectancy at birth in all countries included

Figure 1 Perivenous distribution of multiple sclerosis lesions

Nat. Rev. Neurol. doi: /nrneurol

Figure 2 The US Centers for Disease Control and

Figure 4 Time course of the development of physiological changes

Nat. Rev. Neurol. doi: /nrneurol

Nat. Rev. Neurol. doi: /nrneurol

Figure 8 Implanted devices for the management of heart failure

Figure 2 Bad-metal behaviour and electron correlations

Nat. Rev. Neurol. doi: /nrneurol

Nat. Rev. Neurol. doi: /nrneurol

Figure 3 Proportion of patients for whom NEDA

Figure 5 Number of AHSCT procedures for

Figure 4 Neuromyelitis optica spectrum disorder brain lesions

Nat. Rev. Neurol. doi: /nrneurol

Figure 3 Characterization of anatomical damage

Figure 1 Allele frequency and effect size for ALS-associated genes

Nat. Rev. Neurol. doi: /nrneurol

Figure 3 Hypothetical mechanisms of smoking-associated

Nat. Rev. Urol. doi: /nrurol

Nat. Rev. Neurol. doi: /nrneurol

Figure 2 Algorithm for immunosuppressive treatment

Figure 1 Principles of therapeutic ultrasound

Figure 4 Flow chart of the MDS MSA Study Group aims

Figure 3 Genetic pleiotropy in ALS

Nat. Rev. Neurol. doi: /nrneurol

Figure 1 Evolution of multiple sclerosis

REFLEX and REFLEXION study design.

Nat. Rev. Neurol. doi: /nrneurol

Figure 3 Stroke-related deaths and DALYs by country development status

Figure 2 Age-specific prevalence of common comorbidities

Figure 2 Primary and secondary outcomes reported in multiple sclerosis (MS) disease-modifying therapy (DMT) clinical trials Primary and secondary outcomes.

Figure 6 Combining population-wide and high-risk strategies

Nat. Rev. Neurol. doi: /nrneurol

Figure 2 Logistical requirements for autologous

Figure 3 Potential interplay between physiological

Nat. Rev. Neurol. doi: /nrneurol

Figure 4 Diagnosing neuropathic pain

Pseudoptosis. Pseudoptosis. This man presented with photophobia and difficulty elevating the right side of his forehead. The photograph shows his normal.

Nat. Rev. Neurol. doi: /nrneurol

Figure 1 Timing of the effects of deep brain stimulation

Figure 1 A large number of genes are potentially associated with CIPN

Nat. Rev. Neurol. doi: /nrneurol

Figure 7 Prototypes of topological mechanical metamaterials

Figure 3 Rett syndrome severity and age at diagnosis by mutation type

Nat. Rev. Neurol. doi: /nrneurol

Figure 5 Pairwise correlations between selected patient-reported outcomes and performance tests in patients with MS (A) The number of pairwise correlations.

Figure 4 4D printing schemes and time-evolving structure geometries

Figure 7 VEGF as a mediator of neuroinflammatory disease

Nat. Rev. Neurol. doi: /nrneurol

Figure 2 Network connections of the hypothalamus

The superior quality of MRI over CT is demonstrated in this figure.

Sample MR images obtained acutely from patients 1 to 6: axial T2 weighted (DWI in case 4) on the left, coronal FLAIR on the right of each panel. Sample.

Illustration of the volumetric measures and correspondent anatomy.

Clinical overall score (COS), (A); cold detection thresholds (CDT), (B); warm detection thresholds (WDT), (C); and vibration thresholds (VT), (D) in patients.

Figure 2 Time from incident ADS event to MS diagnosis

Progression of autonomic symptoms including hypohidrosis (A), faintness (B), syncope (C), constipation (D), urinary dysfunction (E), and respiratory disturbance.

Examples of the visual rating scale for the medial and lateral temporal lobe on MR coronal images displayed conventionally with the letter on the right.

(A) High intensity lesions in the left dorsolateral midbrain on T2 weighted magnetic resonance imaging in case 1. (A) High intensity lesions in the left.

Nat. Rev. Mater. doi: /natrevmats

Histograms showing periods until an improvement of one Hughes grade from onset. Histograms showing periods until an improvement of one Hughes grade from.

Typical mean functional strength (where maximum function scores 5, and minimum scores zero; arithmetic mean of several activities plotted) against serum.

Kaplan-Meier table analysis of patients with corticobasal degeneration after onset of symptoms; the y axis refers to proportion of patients who are alive.

Axial magnetic resonance imaging (MRI) of a 30 year old man with relapsing remitting multiple sclerosis (MS) showing multiple periventricular lesions:

Flow of recruitment: the screening and enrolment process for a 6-week randomised double-blind placebo-controlled feasibility trial in people with multiple.

Presentation transcript:

Figure 1 Clinical correlates of neurodegeneration in MS Part a adapted by permission from BMJ Publishing Group Limited. J. Neurol. Neurosurg. Psychiatry, Scalfari, A. et al., 85, 67–75, © 2013. Part b: Scalfari, A. et al., The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability, Brain 133 (Pt 7) (2010), 1914–1929 by permission of Oxford University Press Friese, M. A. et al. (2014) Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis Nat. Rev. Neurol. doi:10.1038/nrneurol.2014.37