Prospective Study of Motor, Sensory, Psychologic, and Autonomic Functions in Patients With Irritable Bowel Syndrome Michael Camilleri, Sanna McKinzie,

Slides:

Advertisements

Similar presentations

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta- analysis Eline J.C.A. Kamp, John S. Kane, Alexander C. Ford Clinical Gastroenterology.

Advertisements

2015 James W. Freston Single Topic Conference: A Renaissance in the Understanding and Management of Irritable Bowel Syndrome Lin Chang, Margaret M. Heitkemper,

MiraLAX Is Not as Effective as GoLytely in Bowel Cleansing Before Screening Colonoscopies Michael Hjelkrem, Joel Stengel, Mark Liu, David P. Jones, Stephen.

Risk of Neoplasia After Colectomy in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis Lauranne A.A.P. Derikx, Loes H.C.

Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea Banny S. Wong, Michael Camilleri, Paula Carlson, Sanna McKinzie,

Colonic Transit and Bile Acid Synthesis or Excretion in Patients With Irritable Bowel Syndrome–Diarrhea Without Bile Acid Malabsorption Cédric Peleman,

Abnormal Liver Tests and Fatty Liver on Ultrasound

Saurabh Dawra, Vishal Sharma, Usha Dutta

Prevalence, Characteristics, and Impact of Bloating Symptoms in Patients With Irritable Bowel Syndrome Yehuda Ringel, Rachel E. Williams, Linda Kalilani,

Charles D. Gerson, Mary-Joan Gerson

Patient-Reported Outcomes for Irritable Bowel Syndrome Are Associated With Patients' Severity Ratings of Gastrointestinal Symptoms and Psychological Factors

Efficacy of a Chinese Herbal Medicine in Providing Adequate Relief of Constipation- predominant Irritable Bowel Syndrome: A Randomized Controlled Trial

Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea Banny S. Wong, Michael Camilleri, Paula Carlson, Sanna McKinzie,

Treatment of Esophageal (Noncardiac) Chest Pain: An Expert Review

Shou–Jiang Tang, Feriyl Bhaijee

Katsunori Matsueda, Tatsuya Toyokawa

A Shocking Cystory Clinical Gastroenterology and Hepatology

Effect of Alvimopan and Codeine on Gastrointestinal Transit: A Randomized Controlled Study Jonathan Gonenne, Michael Camilleri, Irene Ferber, Duane Burton,

A Stable Isotope Breath Test With a Standard Meal for Abnormal Gastric Emptying of Solids in the Clinic and in Research Lawrence A. Szarka, Michael Camilleri,

Immune Reconstitution Inflammatory Syndrome of the Small Bowel in a Human Immunodeficiency Virus–Negative Patient Severin Daum, Christoph Loddenkemper,

Prevalence of Irritable Bowel Syndrome–type Symptoms in Patients With Celiac Disease: A Meta-analysis Anita Sainsbury, David S. Sanders, Alexander C.

Volume 139, Issue 5, Pages e1 (November 2010)

Negative Effects on Psychological Health and Quality of Life of Genuine Irritable Bowel Syndrome–type Symptoms in Patients With Inflammatory Bowel Disease

Eamonn M.M. Quigley Clinical Gastroenterology and Hepatology

Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial Andres Acosta, Michael Camilleri,

Metoclopramide Nasal Spray Reduces Symptoms of Gastroparesis in Women, but not Men, With Diabetes: Results of a Phase 2B Randomized Study Henry P. Parkman,

Functional Dyspepsia Is Associated With Sleep Disorders

Activity-Based Costing and Management in a Hospital-Based GI Unit

The Ghrelin Agonist RM-131 Accelerates Gastric Emptying of Solids and Reduces Symptoms in Patients With Type 1 Diabetes Mellitus Andrea Shin, Michael.

Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome

Michael Hjelkrem, Joel Stengel, Mark Liu, David P. Jones, Stephen A

AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review Jean-Frederic Colombel,

Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea Reginald V. Fant,

Millie D. Long, Hans H. Herfarth, Clare A. Pipkin, Carol Q

Leon P. McLean, Jonathan S. Chun, Raymond K. Cross

A Comprehensive Self-Management Irritable Bowel Syndrome Program Produces Sustainable Changes in Behavior After 1 Year Jasmine K. Zia, Pamela Barney,

Rohan M. Modi, Christina A. Arnold, Peter P. Stanich

Effects of 5-Hydroxytryptamine (Serotonin) Type 3 Antagonists on Symptom Relief and Constipation in Nonconstipated Irritable Bowel Syndrome: A Systematic.

Abnormal Liver Tests and Fatty Liver on Ultrasound

Effects of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation: A Meta-analysis Elizabeth J. Videlock, Vivian.

A Prospective Evaluation of Undiagnosed Joint Hypermobility Syndrome in Patients With Gastrointestinal Symptoms Asma Fikree, Rodney Grahame, Rubina Aktar,

Michael Camilleri, Allen W. Mangel, Sheri E. Fehnel, Douglas A

Dushyant Singh, Reetu Singh, Wendell K. Clarkston

Kara Bradford, Wendy Shih, Elizabeth J. Videlock, Angela P

Evaluation of the Patient-Reported Outcomes Measurement Information System in a Large Cohort of Patients With Inflammatory Bowel Diseases Michael D.

Volume 141, Issue 5, Pages e7 (November 2011)

Short-term and Long-term Efficacy of Psychological Therapies for Irritable Bowel Syndrome: A Systematic Review and Meta-analysis Kelsey T. Laird, Emily.

Bowel Urgency in Patients With Irritable Bowel Syndrome

Coping Skills Are Associated With Gastrointestinal Symptom Severity and Somatization in Patients With Irritable Bowel Syndrome Katarina Wilpart, Hans.

Rebecca M. Lovell, Alexander C. Ford

A Young Woman With Gallstone Pancreatitis and Abnormal Liver Tests: When Is Endoscopic Retrograde Cholangiopancreatography Needed? Andrew D. Rhim, Michael.

Volume 131, Issue 5, Pages (November 2006)

Effect of renzapride on transit in constipation-predominant irritable bowel syndrome Michael Camilleri, Sanna McKinzie, Jean Fox, Amy Foxx-orenstein,

Effects of Different Coping Strategies on Physical and Mental Health of Patients With Irritable Bowel Syndrome Lilian Dindo, PhD Clinical Gastroenterology.

Risk of Irritable Bowel Syndrome After an Episode of Bacterial Gastroenteritis in General Practice: Influence of Comorbidities Ana Ruigómez, Luis Alberto.

Effects of venlafaxine, buspirone, and placebo on colonic sensorimotor functions in healthy humans Heather J. Chial, Michael Camilleri, Irene Ferber,

Nicolas Williet, William J. Sandborn, Laurent Peyrin–Biroulet

Effects of Chenodeoxycholate and a Bile Acid Sequestrant, Colesevelam, on Intestinal Transit and Bowel Function Suwebatu T. Odunsi–Shiyanbade, Michael.

Alteration of Gastric Functions and Candidate Genes Associated With Weight Reduction in Response to Sibutramine Maria I. Vazquez Roque, Michael Camilleri,

Severe irritable bowel and functional abdominal pain syndromes: Managing the patient and health care costs George F. Longstreth, Douglas A. Drossman

Emma Janet Castillo, Michael Camilleri, G. Richard Locke, Duane D

Effects of Chenodeoxycholate and a Bile Acid Sequestrant, Colesevelam, on Intestinal Transit and Bowel Function Suwebatu T. Odunsi–Shiyanbade, Michael.

GI Bleeding, Colon Varicosities, and Visceral Enlargement as a Manifestation of Klippel– Trenaunay Syndrome Fnu Deepinder Clinical Gastroenterology and.

Rintaro Hashimoto, Akimichi Chonan

Adverse Outcomes: Why Bad Things Happen to Good People

Kevin P. Quinn, James H. Tabibian, Seth Sweetser

Rintaro Hashimoto, Akimichi Chonan

Subcapsular Hepatic Fluid Collection Caused by Cardiac Dysfunction

Self-Administered Cognitive Behavior Therapy for Moderate to Severe Irritable Bowel Syndrome: Clinical Efficacy, Tolerability, Feasibility Jeffrey M.

Choosing Wisely and the Perceived Drivers of Endoscopy Use

Presentation transcript:

Prospective Study of Motor, Sensory, Psychologic, and Autonomic Functions in Patients With Irritable Bowel Syndrome Michael Camilleri, Sanna McKinzie, Irene Busciglio, Phillip A. Low, Seth Sweetser, Duane Burton, Kari Baxter, Michael Ryks, Alan R. Zinsmeister Clinical Gastroenterology and Hepatology Volume 6, Issue 7, Pages 772-781.e5 (July 2008) DOI: 10.1016/j.cgh.2008.02.060 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 SCL-90 mean T scores. Note there are statistically significant differences in anxiety, depression, somatization, general severity index (gsi), and positive symptom total (pst). Clinical Gastroenterology and Hepatology 2008 6, 772-781.e5DOI: (10.1016/j.cgh.2008.02.060) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 Comparison of colonic GC at 24 and 48 hours in healthy controls and IBS patients with different types of bowel dysfunction. #P = .078; *P < .05; **P = .056. Clinical Gastroenterology and Hepatology 2008 6, 772-781.e5DOI: (10.1016/j.cgh.2008.02.060) Copyright © 2008 AGA Institute Terms and Conditions

Figure 3 Percentage of participants in each group reaching threshold for first sensation, gas, urgency, and pain in response to step-wise increase in intraballoon pressure; note the significant overlap and lack of any significant differences in any group or any sensation relative to controls. Clinical Gastroenterology and Hepatology 2008 6, 772-781.e5DOI: (10.1016/j.cgh.2008.02.060) Copyright © 2008 AGA Institute Terms and Conditions

Figure 4 Sensory ratings of participants in each group for urgency and pain in response to random-order, phasic increase in intraballoon pressure; note the significant overlap for the sensation of pain and the lower sensory ratings for urgency in IBS-C (P = .04 vs healthy controls). Clinical Gastroenterology and Hepatology 2008 6, 772-781.e5DOI: (10.1016/j.cgh.2008.02.060) Copyright © 2008 AGA Institute Terms and Conditions

Supplementary Figure Overlap of abnormal transit and increased sensation in patients with IBS. Clinical Gastroenterology and Hepatology 2008 6, 772-781.e5DOI: (10.1016/j.cgh.2008.02.060) Copyright © 2008 AGA Institute Terms and Conditions