Early elevation of cardiac troponin I is predictive of short-term outcome in neonates and infants with coronary anomalies or reduced ventricular mass.

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Presentation transcript:

Early elevation of cardiac troponin I is predictive of short-term outcome in neonates and infants with coronary anomalies or reduced ventricular mass undergoing cardiac surgery  Mirela Bojan, MD, MSc, Harlinde Peperstraete, MD, Marc Lilot, MD, Stéphanie Vicca, PharmD, PhD, Philippe Pouard, MD, Pascal Vouhé, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 144, Issue 6, Pages 1436-1444 (December 2012) DOI: 10.1016/j.jtcvs.2012.05.034 Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Cardiac troponin I concentrations measured within the first week of surgery in patients with cardiopulmonary bypass. The composite outcome included 30-day mortality and severe morbidity. Severe morbidity was accounted for by an extremely low cardiac output necessitating extracorporeal membrane oxygenation and/or leading to renal injury requiring peritoneal dialysis, and/or by a very long length of intensive care unit stay (the 95th percentile per procedure). Mean values are shown using the LOESS (locally weighted scatterplot smoother). Shading lines show the first 24 hours after surgery. VSD, Ventricular septal defect; ASO, arterial switch operation; HLHS, hypoplastic left heart syndrome; TAPVC, total anomalous pulmonary venous connection; ALCAPA, anomalous left coronary artery from the pulmonary artery. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1436-1444DOI: (10.1016/j.jtcvs.2012.05.034) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Cardiac troponin I concentrations measured within the first week after surgery in patients without cardiopulmonary bypass. The composite outcome included 30-day mortality and severe morbidity. Severe morbidity was accounted for by an extremely low cardiac output necessitating extracorporeal membrane oxygenation and/or leading to renal injury requiring peritoneal dialysis, and/or by a very long length of stay in the intensive care unit (the 95th percentile per procedure). Mean values are shown using the LOESS (locally weighted scatterplot smoother). Shading lines show the first 24 hours after surgery. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 1436-1444DOI: (10.1016/j.jtcvs.2012.05.034) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions