AID for Innate Immunity to Retroviral Transformation

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AID for Innate Immunity to Retroviral Transformation Mark S. Schlissel, Tracy C. Kuo  Immunity  Volume 24, Issue 6, Pages 671-672 (June 2006) DOI: 10.1016/j.immuni.2006.06.005 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 Cytidine Deaminase Activities in Animal Cells Cytidine deaminases (CDAs), long known to be involved in nucleotide salvage pathways, have more recently been found to play key roles in gene expression, anti-viral immunity, and immunoglobulin gene diversification (SHM, somatic hypermutation; CSR, class-switch recombination). Vif is an HIV gene product which interferes with APOBEC3 activity. Immunity 2006 24, 671-672DOI: (10.1016/j.immuni.2006.06.005) Copyright © 2006 Elsevier Inc. Terms and Conditions

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