Soluble ST2 Is a Marker for Acute Cardiac Allograft Rejection

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Presentation transcript:

Soluble ST2 Is a Marker for Acute Cardiac Allograft Rejection Domingo A. Pascual-Figal, MD, PhD, Iris P. Garrido, MD, Rosa Blanco, MD, Alfredo Minguela, PhD, Antonio Lax, PhD, Jordi Ordoñez- Llanos, PhD, Antoni Bayes-Genis, MD, PhD, Mariano Valdés, MD, PhD, Stephanie A. Moore, MD, James L. Januzzi, MD The Annals of Thoracic Surgery Volume 92, Issue 6, Pages 2118-2124 (December 2011) DOI: 10.1016/j.athoracsur.2011.07.048 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 sST2 concentrations as a function of histologic grade of rejection severity (International Society of Heart and Lung Transplantation grading system; sST2 = soluble ST2). The Annals of Thoracic Surgery 2011 92, 2118-2124DOI: (10.1016/j.athoracsur.2011.07.048) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Serial changes of sST2 concentrations (before, during, and after rejection) in all patients (n = 26). (A) Patients with biopsy-proven rejection (n = 12). (B) Data shown are median and interquartile ranges. The p value refers to changes within subjects across the 3 measurements. (sST2 = soluble ST2.) The Annals of Thoracic Surgery 2011 92, 2118-2124DOI: (10.1016/j.athoracsur.2011.07.048) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions