Sarcoid-Like Reaction Mimics Progression of Disease After Induction Chemotherapy for Lung Cancer Masayuki Chida, MD, PhD, Takashi Inoue, MD, Koichi Honma,

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Sarcoid-Like Reaction Mimics Progression of Disease After Induction Chemotherapy for Lung Cancer Masayuki Chida, MD, PhD, Takashi Inoue, MD, Koichi Honma, MD, PhD, Koji Murakami, MD, PhD The Annals of Thoracic Surgery Volume 90, Issue 6, Pages 2031-2033 (December 2010) DOI: 10.1016/j.athoracsur.2010.06.014 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Computed tomographic scan images of a primary tumor in the right lower lobe and a pretracheal lymph node (A) before and (B) after induction chemotherapy. (A) Enlarged pretracheal lymph node (left) and nodular tumor in S6 (right). (B) Induction chemotherapy resulted in reduction of both the tumor (left) and pretracheal lymph node (right). The Annals of Thoracic Surgery 2010 90, 2031-2033DOI: (10.1016/j.athoracsur.2010.06.014) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Fluorodeoxyglucose (FDG) positron emission tomographic images of lymph nodes (A) before and (B) after induction chemotherapy. (A) A single pretracheal lymph node diagnosed as pN2 by needle biopsy using endobronchial ultrasound, showing positive accumulation of FDG. (B) Multiple mediastinal and bilateral hilar lymph nodes showing positive accumulation of FDG. The Annals of Thoracic Surgery 2010 90, 2031-2033DOI: (10.1016/j.athoracsur.2010.06.014) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A) Sarcoid granulomas in a dissected lymph node specimen. (Hematoxylin and eosin; ×50.) (B) Viable cancer cells in the pretracheal lymph node (Hematoxylin and eosin; ×100.) The Annals of Thoracic Surgery 2010 90, 2031-2033DOI: (10.1016/j.athoracsur.2010.06.014) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions