Patients undergoing infrainguinal bypass to treat atherosclerotic vascular disease are underprescribed cardioprotective medications: effect on graft patency,

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Presentation transcript:

Patients undergoing infrainguinal bypass to treat atherosclerotic vascular disease are underprescribed cardioprotective medications: effect on graft patency, limb salvage, and mortality Peter K Henke, MD, Susan Blackburn, MBA, Mary C Proctor, MS, Jeri Stevens, MS, Debabrata Mukherjee, MD, Sanjay Rajagopalin, MD, Gilbert R Upchurch, MD, James C Stanley, MD, Kim A Eagle, MD Journal of Vascular Surgery Volume 39, Issue 2, Pages 357-365 (February 2004) DOI: 10.1016/j.jvs.2003.08.030

Fig 1 Cardiovascular medication use in a population of patients undergoing infrainguinal bypass procedures over 5 years. AP, Antiplatelet therapy; AC, anticoagulant therapy; BB, β-blocker use; ACEI, angiotensin converting enzyme inhibitor use; MV, multivitamin. Journal of Vascular Surgery 2004 39, 357-365DOI: (10.1016/j.jvs.2003.08.030)

Fig 2 Kaplan-Meier plot depicts overall survival over time. Dashed lines, 95% confidence intervals surrounding the main plot. Journal of Vascular Surgery 2004 39, 357-365DOI: (10.1016/j.jvs.2003.08.030)

Fig 3 Kaplan-Meier plot compares survival in patients who were taking angiotensin converting enzyme inhibitors with those who were not taking this medication. The difference was significant by log-rank test, at P = .05. Dashed line, Portion of plot where standard error is greater than 10%. Journal of Vascular Surgery 2004 39, 357-365DOI: (10.1016/j.jvs.2003.08.030)

Fig 4 Kaplan-Meier plot compares survival in patients who were taking aspirin with those who were not taking this medication. A trend was observed, but the difference did not reach significance (P = .067, log rank test). Dashed line, Portion of plot where standard error is greater than 10%. Journal of Vascular Surgery 2004 39, 357-365DOI: (10.1016/j.jvs.2003.08.030)