Arterial Stiffness Assessed by Digital Volume Pulse Correlates With Comorbidity in Patients With ESRD Daniel Sollinger, MD, Markus G. Mohaupt, MD, Albina.

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Arterial Stiffness Assessed by Digital Volume Pulse Correlates With Comorbidity in Patients With ESRD Daniel Sollinger, MD, Markus G. Mohaupt, MD, Albina Wilhelm, MD, Dominik Uehlinger, MD, Felix J. Frey, MD, Ute Eisenberger, MD American Journal of Kidney Diseases Volume 48, Issue 3, Pages 456-463 (September 2006) DOI: 10.1053/j.ajkd.2006.05.014 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 1 Calculation of SIDVP by using the DVP waveform. American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 2 Bland-Altman plot showing the difference between SIDVP minus PWV measurements as a function of the mean of both measurements. Dashed lines, mean difference ± SD; ▴, TX recipients; ■, HD patients. American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 3 SIDVP as a function of age in (A) TX recipients and (B) HD patients. American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 4 Residuals (ΔSIDVP) of SIDVP as a function of age in TX recipients and HD patients. Individual dots are the difference (residuals) between expected and actual SIDVP. The zero line represents the theoretically expected age-dependent value (SIexpect) derived from Fig 3 A and B. Dashed lines are given by the cutoff values of ± 0.7 m/s, as rationalized in Results. American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 5 Comorbid status and groups of residuals. Group 1, less than −0.7 m/s (11 HD patients, 11 TX recipients); group 2, +0.7 m/s or less and −0.7 m/s or greater (10 HD patients, 15 TX recipients); group 3, greater than +0.7 m/s (15 HD patients, 17 TX recipients); and group 4, SIDVP not measurable (12 HD patients, 3 TX recipients). American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 6 Receiver operating characteristic curves comparing SIDVP and PWV measurements for the group with high comorbid risk. Comparison of areas under the curves tended to be different (P = 0.08). Areas under the curve for SIDVP and PWV were 0.76 (95% confidence interval, 0.66 to 0.87) and 0.66 (95% confidence interval, 0.52 to 0.80), respectively. American Journal of Kidney Diseases 2006 48, 456-463DOI: (10.1053/j.ajkd.2006.05.014) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions