Mechanisms of FSH synthesis: what we know, what we don't, and why you should care  Daniel J. Bernard, Ph.D., Jérôme Fortin, B.Sc., Ying Wang, B.Sc., Pankaj Lamba, M.D.  Fertility and Sterility  Volume 93, Issue 8, Pages 2465-2485 (May 2010) DOI: 10.1016/j.fertnstert.2010.03.034 Copyright © 2010 Terms and Conditions

Figure 1 Alignment of proximal Fshb/FSHB promoters in pig, sheep, human, mouse, and rat. The proximal 400 bp from the 5′ flanking regions of the Fshb/FSHB genes in the indicated species were aligned using ClustalW2 (http://www.ebi.ac.uk/Tools/clustalw2/index.html). Defined cis-elements (as described in the text) are labeled and boxed (with the exception of the PBX/PREP site in sheep, which is marked with a bracket to avoid cluttering the figure). Some nucleotides are boxed in gray to reflect differences from the experimentally defined cis-element in other species. Nucleotides are numbered at the right relative to the start of transcription. Nucleotides conserved across species are marked with an asterisk (∗) and gaps (−) have been introduced to facilitate the alignment. Fertility and Sterility 2010 93, 2465-2485DOI: (10.1016/j.fertnstert.2010.03.034) Copyright © 2010 Terms and Conditions