The laws of acute otitis media

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Presentation transcript:

The laws of acute otitis media Christopher J Harrison, MD Primary Care: Clinics in Office Practice Volume 30, Issue 1, Pages 109-135 (March 2003) DOI: 10.1016/S0095-4543(03)00004-6

Fig. 1 Day after cessation of antibiotics. Proportions of episodes of acute otitis media caused by new (gray) vs. original (black) pathogens by time after stopping antibiotics (Adapted from Dagan R, Leibovitz E. Bacterial eradication in the treatment of otitis media. The Lancet Infect Dis 2002:2;593–604. Primary Care: Clinics in Office Practice 2003 30, 109-135DOI: (10.1016/S0095-4543(03)00004-6)

Fig. 2 PK/PD efficiacy for amoxicillin at different doses. (From Harrison C, et al. Diagnosis and management of acute otitis media, Pediatr Infect Dis 1998:17;657–8; with permission.) Primary Care: Clinics in Office Practice 2003 30, 109-135DOI: (10.1016/S0095-4543(03)00004-6)