Vasiliki V. Georgiopoulou, MD, Andreas P. Kalogeropoulos, MD, Bruce M

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Lung Function and Risk for Heart Failure Among Older Adults: The Health ABC Study Vasiliki V. Georgiopoulou, MD, Andreas P. Kalogeropoulos, MD, Bruce M. Psaty, MD, PhD, Nicolas Rodondi, MD, MAS, Douglas C. Bauer, MD, Abida B. Butler, MD, Annemarie Koster, PhD, Andrew L. Smith, MD, Tamara B. Harris, MD, MS, Anne B. Newman, MD, MPH, Stephen B. Kritchevsky, PhD, Javed Butler, MD, MPH The American Journal of Medicine Volume 124, Issue 4, Pages 334-341 (April 2011) DOI: 10.1016/j.amjmed.2010.12.006 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Flowchart of participant selection for the current analysis. The American Journal of Medicine 2011 124, 334-341DOI: (10.1016/j.amjmed.2010.12.006) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 2 Annualized risk of incident heart failure for participants with normal versus abnormal lung function tests at baseline, adjusted for predictors of heart failure and body mass index. Smoothed hazard estimate was obtained using an Epanechnikov kernel. Although the absolute annualized risk increases from year 1 to year 5 before reaching a plateau in both groups, the relative risk remains stable over time. The American Journal of Medicine 2011 124, 334-341DOI: (10.1016/j.amjmed.2010.12.006) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 3 Kaplan-Meier rates of incident heart failure by baseline lung function status in sex and race subgroups, adjusted for predictors of heart failure and body mass index. The American Journal of Medicine 2011 124, 334-341DOI: (10.1016/j.amjmed.2010.12.006) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 4 Unadjusted incident heart failure rates according to baseline forced expiratory volume in 1st second (FEV1) and forced vital capacity (FVC) values. Rates are expressed in cases per 1000 person-years. The American Journal of Medicine 2011 124, 334-341DOI: (10.1016/j.amjmed.2010.12.006) Copyright © 2011 Elsevier Inc. Terms and Conditions