The factor V Leiden mutation: Spectrum of thrombotic events and laboratory evaluation Franklin A. Bontempo, MD, Andrea Cortese Hassett, PhD, Hawazin Faruki,

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Presentation transcript:

The factor V Leiden mutation: Spectrum of thrombotic events and laboratory evaluation Franklin A. Bontempo, MD, Andrea Cortese Hassett, PhD, Hawazin Faruki, DrPH, David L. Steed, MD, Marshall W. Webster, MD, Michel S. Makaroun, MD Journal of Vascular Surgery Volume 25, Issue 2, Pages 271-276 (February 1997) DOI: 10.1016/S0741-5214(97)70348-3 Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Site of cleavage (arrow) of the 220bp segment of the normal and mutant factor V gene. Journal of Vascular Surgery 1997 25, 271-276DOI: (10.1016/S0741-5214(97)70348-3) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Age distribution at diagnosis of 107 patients with factor V Leiden mutation and thrombotic events (entire column) and the 17 patients with myocardial infarction or stroke/transient ischemic attack (shaded part). Journal of Vascular Surgery 1997 25, 271-276DOI: (10.1016/S0741-5214(97)70348-3) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions