Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia Leena Kainulainen, MD, Tytti Vuorinen, MD,

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Presentation transcript:

Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia Leena Kainulainen, MD, Tytti Vuorinen, MD, Kaisu Rantakokko-Jalava, MD, Riikka Österback, MSc, Olli Ruuskanen, MD Journal of Allergy and Clinical Immunology Volume 126, Issue 1, Pages 120-126 (July 2010) DOI: 10.1016/j.jaci.2010.04.016 Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Symptoms, infections, microbiological findings, antibiotic treatments, and immunoglobulin infusions over 12 months in 12 patients. Journal of Allergy and Clinical Immunology 2010 126, 120-126DOI: (10.1016/j.jaci.2010.04.016) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Phylogenetic tree of rhinovirus partial 5′ NCR sequences of nasal and sputum specimens of a patient with XLA for a 5-month period and rhinovirus prototypes HRV4, HRV21, and HRV89 (GenBank accession numbers DQ473490, FJ445121, and FJ445184). Scale bars indicate nucleotide substitutions per position. Journal of Allergy and Clinical Immunology 2010 126, 120-126DOI: (10.1016/j.jaci.2010.04.016) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions