A Randomized Controlled Trial of Postthoracotomy Pulmonary Rehabilitation in Patients with Resectable Lung Cancer Jos A. Stigt, MD, Steven M. Uil, MSc,

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Presentation transcript:

A Randomized Controlled Trial of Postthoracotomy Pulmonary Rehabilitation in Patients with Resectable Lung Cancer Jos A. Stigt, MD, Steven M. Uil, MSc, Susanne J.H. van Riesen, Frans J.N.A. Simons, MD, Monique Denekamp, Ghada M. Shahin, MD, Harry J.M. Groen, MD, PhD Journal of Thoracic Oncology Volume 8, Issue 2, Pages 214-221 (February 2013) DOI: 10.1097/JTO.0b013e318279d52a Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Study design. NSCLC, non–small-cell lung cancer; R, randomization; 6MWD, 6-minute walking distance; QOL, quality of life; D, discharge from hospital. Journal of Thoracic Oncology 2013 8, 214-221DOI: (10.1097/JTO.0b013e318279d52a) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Consort flow chart. 6MWD, 6-minute walking distance; QOL, quality of life. Journal of Thoracic Oncology 2013 8, 214-221DOI: (10.1097/JTO.0b013e318279d52a) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Quality of life and impact of pain on quality of life in resectable lung cancer patients treated in a postthoracotomy rehabilitation program (actives) or receiving usual care (controls). A, SGRQ. B, SF-36 role physical. C, SF-36 general health.D, MPQ-DLV QLI. SGRG, St. George's Respiratory Questionnaire; SF-36, Short Form health survey; MPQ-DLV QLI, Dutch Version of the McGill Pain Questionnaire quality of life index; BD, before discharge. Error bars represent 95% confidence intervals. Journal of Thoracic Oncology 2013 8, 214-221DOI: (10.1097/JTO.0b013e318279d52a) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Exercise tolerance in patients treated in a pulmonary rehabilitation program (actives) compared with usual care (controls) measured with the 6-minute walking distance, before and 3 months after discharge from hospital. Only the results of patients with a paired (preoperative/postoperative) 6MWD test were used. 6-MWD, 6-minute walking distance. Error bars represent 95% confidence intervals. Journal of Thoracic Oncology 2013 8, 214-221DOI: (10.1097/JTO.0b013e318279d52a) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Sensation of pain and use of analgesics in resectable lung cancer patients treated in a postthoracotomy rehabilitation program (actives) or receiving usual care (controls). A, MPQ-DLV PRI total. B, MPQ-DLV VAS present. C, SF-36 pain. D, use of analgesics. MPQ-DLV PRI total, total pain rating index of the Dutch version of the McGill Pain Questionnaire; MPQ-DLV VAS, Dutch version of the McGill Pain Questionnaire Visual Analogue Scale; SF-36, Short Form health survey; BS, before surgery; BD, before discharge. Error bars represent 95% confidence intervals. Journal of Thoracic Oncology 2013 8, 214-221DOI: (10.1097/JTO.0b013e318279d52a) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions