Anthony P. Furnary, MDa, Juan-Carlos Chachques, MD, PhDb, Luiz F. P

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Presentation transcript:

Long-term outcome, survival analysis, and risk stratification of dynamic cardiomyoplasty Anthony P. Furnary, MDa, Juan-Carlos Chachques, MD, PhDb, Luiz F.P. Moreira, MDc, Gary L. Grunkemeier, PhDa, Jeffrey S. Swanson, MDa, Noedir Stolf, MDc, Sam Haydar, MDa, Christoph Acar, MDb, Albert Starr, MDa, Adib D. Jatene, MDc, Alain F. Carpentier, MD, PhDb The Journal of Thoracic and Cardiovascular Surgery Volume 112, Issue 6, Pages 1640-1650 (December 1996) DOI: 10.1016/S0022-5223(96)70023-5 Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 1 Histogram comparing preoperative and 6 and 12 month postoperative left ventricular ejection fractions (LVEF). Hatched bars represent one standard error of measurement. NS, Not significant. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 2 Stacked histograms of mean NYHA functional class before the operation and 6 and 12 months after the operation. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 3 Kaplan-Meier survival curve for 127 patients who underwent cardiomyoplasty between 1985 and 1994. Numbers above the curve represent the number of patients surviving to that point in time. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 4 Relationship of composite risk score generated from the Cox regression model (y-axis) to actual survival after cardiomyoplasty (x-axis). The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 5 Effect of four independent predictors of poor long-term survival that were identified by the Cox proportional hazards model. In each of these figures the survival of patients with and without the respective risk factor is compared. These predictors include IABP use (A), oxygen consumption (VO2 ) (B), atrial fibrillation (AFIB) (C), and pulmonary capillary wedge pressure (D). Note IABP and oxygen consumption effect on procedural deaths and effect of atrial fibrillation and pulmonary capillary wedge pressure on late deaths. The p values are based on the log-rank test statistic. NSR, Normal sinus rhythm. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 5 Effect of four independent predictors of poor long-term survival that were identified by the Cox proportional hazards model. In each of these figures the survival of patients with and without the respective risk factor is compared. These predictors include IABP use (A), oxygen consumption (VO2 ) (B), atrial fibrillation (AFIB) (C), and pulmonary capillary wedge pressure (D). Note IABP and oxygen consumption effect on procedural deaths and effect of atrial fibrillation and pulmonary capillary wedge pressure on late deaths. The p values are based on the log-rank test statistic. NSR, Normal sinus rhythm. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 5 Effect of four independent predictors of poor long-term survival that were identified by the Cox proportional hazards model. In each of these figures the survival of patients with and without the respective risk factor is compared. These predictors include IABP use (A), oxygen consumption (VO2 ) (B), atrial fibrillation (AFIB) (C), and pulmonary capillary wedge pressure (D). Note IABP and oxygen consumption effect on procedural deaths and effect of atrial fibrillation and pulmonary capillary wedge pressure on late deaths. The p values are based on the log-rank test statistic. NSR, Normal sinus rhythm. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 5 Effect of four independent predictors of poor long-term survival that were identified by the Cox proportional hazards model. In each of these figures the survival of patients with and without the respective risk factor is compared. These predictors include IABP use (A), oxygen consumption (VO2 ) (B), atrial fibrillation (AFIB) (C), and pulmonary capillary wedge pressure (D). Note IABP and oxygen consumption effect on procedural deaths and effect of atrial fibrillation and pulmonary capillary wedge pressure on late deaths. The p values are based on the log-rank test statistic. NSR, Normal sinus rhythm. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 1640-1650DOI: (10.1016/S0022-5223(96)70023-5) Copyright © 1996 Mosby, Inc. Terms and Conditions