Aortic aneurysms in children and young adults with tuberous sclerosis: Report of two cases and review of the literature Corey J. Jost, MDa, Peter Gloviczki,

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Presentation transcript:

Aortic aneurysms in children and young adults with tuberous sclerosis: Report of two cases and review of the literature Corey J. Jost, MDa, Peter Gloviczki, MDa, William D. Edwards, MDb, Anthony W. Stanson, MDc, John W. Joyce, MDd, Peter C. Pairolero, MDa Journal of Vascular Surgery Volume 33, Issue 3, Pages 639-642 (March 2001) DOI: 10.1067/mva.2001.111976 Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 1 CT scan of 9-year-old female demonstrates 3-cm calcified AAA. Journal of Vascular Surgery 2001 33, 639-642DOI: (10.1067/mva.2001.111976) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 2 Transfemoral aortogram from case 1: anterior to posterior view. Used with permission from Rooke T, Joyce JW. Uncommon arteriopathies. Rutherford RB, editor. Vascular surgery. 5th ed. Philadelphia: WB Saunders; 2000. p. 418-34. Journal of Vascular Surgery 2001 33, 639-642DOI: (10.1067/mva.2001.111976) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 3 Photomicrographs of normal abdominal aortic wall (left ) and of aneurysm wall with TS—case 1 (right ) shows all three arterial layers (Verhoff-van Gieson stain; original magnification × 10). Diseased aorta exhibits dysplastic features, marked medial atrophy, fibrosis with focal disruption, prominent intimal hyperplasia, and moderate adventitial fibrosis. Journal of Vascular Surgery 2001 33, 639-642DOI: (10.1067/mva.2001.111976) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 4 CT scan with intravenous contrast 7 years after AAA repair (case 1) shows normal aorta and patent aortic graft. Note calcification of aortic wall around graft. Journal of Vascular Surgery 2001 33, 639-642DOI: (10.1067/mva.2001.111976) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions