Volume 380, Issue 9852, Pages (October 2012)

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Volume 380, Issue 9852, Pages 1491-1497 (October 2012) Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data Prof Mika Kivimäki, PhD, Solja T Nyberg, MSc, G David Batty, PhD, Eleonor I Fransson, PhD, Katriina Heikkilä, PhD, Prof Lars Alfredsson, PhD, Prof Jakob B Bjorner, MD, Marianne Borritz, MD, Hermann Burr, PhD, Annalisa Casini, PhD, Els Clays, PhD, Prof Dirk De Bacquer, PhD, Prof Nico Dragano, PhD, Jane E Ferrie, PhD, Goedele A Geuskens, PhD, Prof Marcel Goldberg, MD, Mark Hamer, PhD, Wendela E Hooftman, PhD, Irene L Houtman, PhD, Matti Joensuu, MSc, Markus Jokela, PhD, Prof France Kittel, PhD, Prof Anders Knutsson, PhD, Prof Markku Koskenvuo, MD, Aki Koskinen, MSc, Anne Kouvonen, PhD, Meena Kumari, PhD, Ida EH Madsen, Prof Michael G Marmot, MD, Martin L Nielsen, MD, Maria Nordin, PhD, Tuula Oksanen, MD, Jaana Pentti, BSc, Prof Reiner Rugulies, PhD, Paula Salo, PhD, Prof Johannes Siegrist, PhD, Archana Singh-Manoux, PhD, Sakari B Suominen, MD, Ari Väänänen, PhD, Prof Jussi Vahtera, MD, Prof Marianna Virtanen, PhD, Prof Peter JM Westerholm, MD, Prof Hugo Westerlund, Marie Zins, MD, Prof Andrew Steptoe, DPh, Prof Töres Theorell, MD The Lancet Volume 380, Issue 9852, Pages 1491-1497 (October 2012) DOI: 10.1016/S0140-6736(12)60994-5 Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 1 Random-effects meta-analysis of the association between job strain and incident coronary heart disease Estimates are adjusted for age and sex. WOLF-S=Work, Lipids, Fibrinogen-Stockholm. IPAW=Intervention Project on Absence and Well-being. WOLF-N=Work, Lipids, Fibrinogen-Norrland. COPSOQ-I=Copenhagen Psychosocial Questionnaire version I. GAZEL=Electricité De France-Gaz De France. POLS=Permanent Onderzoek Leefsituatie. HeSSup=Health and Social Support. DWECS=Danish Work Environment Cohort Study. FPS=Finnish Public Sector Study. NWCS=Netherlands Working Conditions Survey. The Lancet 2012 380, 1491-1497DOI: (10.1016/S0140-6736(12)60994-5) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 2 Association of job strain with incident coronary heart disease in relation to study follow-up periods, adjustments, publication status for data, and geographical region Estimates are adjusted for age and sex unless otherwise stated. Some estimates are further adjusted for SES, health behaviours, and the Framingham score. SES=socioeconomic status. The Lancet 2012 380, 1491-1497DOI: (10.1016/S0140-6736(12)60994-5) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 3 Association of job strain with incident coronary heart disease in subgroups Estimates are adjusted, when appropriate, for age and sex. We excluded events that occurred in the first 3 years of follow-up. The Lancet 2012 380, 1491-1497DOI: (10.1016/S0140-6736(12)60994-5) Copyright © 2012 Elsevier Ltd Terms and Conditions