Extended culture of vitrified–warmed embryos in day-3 embryo transfer cycles: a randomized controlled pilot study Rentao Jin, Xianhong Tong, Limin Wu,

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Presentation transcript:

Extended culture of vitrified–warmed embryos in day-3 embryo transfer cycles: a randomized controlled pilot study Rentao Jin, Xianhong Tong, Limin Wu, Lihua Luo, Hongbing Luan, Guixiang Zhou, Lars Johansson, Yusheng Liu Reproductive BioMedicine Online Volume 26, Issue 4, Pages 384-392 (April 2013) DOI: 10.1016/j.rbmo.2012.12.003 Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Schematic representation of the trial protocol. All embryos were cryopreserved on day 3 of the fresh cycles. In the extended culture group, embryos were warmed on day 2 of progesterone supplementation, cultured overnight and then transferred (at day 4 of preimplantation development). In the control group, embryos were warmed on day 3 of progesterone supplementation and transferred within 2h of warming (at day 3 of preimplantation development). ET=embryo transfer. Reproductive BioMedicine Online 2013 26, 384-392DOI: (10.1016/j.rbmo.2012.12.003) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 CONSORT statement flow diagram. Reproductive BioMedicine Online 2013 26, 384-392DOI: (10.1016/j.rbmo.2012.12.003) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Implantation rates in the EC group according to the cell stage of transferred embryos. Only cycles in which all the transferred embryos were at the same developmental stage were included. n=number of embryos transferred. ∗P<0.05; ∗∗P<0.01. R×C contingency table analysis is adopted by chi-squared tests. Because P<0.05 (P=0.006), a modified chi-squared statistic is applied for further testing within each subject. Reproductive BioMedicine Online 2013 26, 384-392DOI: (10.1016/j.rbmo.2012.12.003) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions