Prognostic implications of pulmonary hypertension in patients with severe aortic stenosis Akin Cam, MD, Sachin S. Goel, MD, Shikhar Agarwal, MD, MPH,

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Prognostic implications of pulmonary hypertension in patients with severe aortic stenosis Akin Cam, MD, Sachin S. Goel, MD, Shikhar Agarwal, MD, MPH, Venu Menon, MD, Lars G. Svensson, MD, PhD, E. Murat Tuzcu, MD, Samir R. Kapadia, MD The Journal of Thoracic and Cardiovascular Surgery Volume 142, Issue 4, Pages 800-808 (October 2011) DOI: 10.1016/j.jtcvs.2010.12.024 Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Kaplan–Meier curves comparing survival in the mild-to-moderate and severe PH groups with AVR (P value using log rank statistic: .8). The Journal of Thoracic and Cardiovascular Surgery 2011 142, 800-808DOI: (10.1016/j.jtcvs.2010.12.024) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Kaplan–Meier curves comparing survival in the AVR and non-AVR groups among patients with severe PH (P value using log rank statistic: .002). The Journal of Thoracic and Cardiovascular Surgery 2011 142, 800-808DOI: (10.1016/j.jtcvs.2010.12.024) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Two-dimensional scatter plot with preoperative mean PAP on the x axis and postoperative mean PAP on the y axis stratified by death. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 800-808DOI: (10.1016/j.jtcvs.2010.12.024) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Multivariate logistic regression analysis for preoperative predictors of reduction in mean PAP. According to the reduction of mean PAP, the entire study population was divided into 2 groups: responders (patients with ≥ 10 mm Hg reduction after AVR) and nonresponders (patients with < 10 mm Hg reduction after AVR). The Journal of Thoracic and Cardiovascular Surgery 2011 142, 800-808DOI: (10.1016/j.jtcvs.2010.12.024) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions