Frozen sections of (A) fetal intestine, (B) tonsil, and (C) mantle cell lymphoma, stained using anti-CD3 (immunoperoxidase; brown) followed by anti-CD5.

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Presentation transcript:

Frozen sections of (A) fetal intestine, (B) tonsil, and (C) mantle cell lymphoma, stained using anti-CD3 (immunoperoxidase; brown) followed by anti-CD5 (immunoalkaline phosphatase; blue). Frozen sections of (A) fetal intestine, (B) tonsil, and (C) mantle cell lymphoma, stained using anti-CD3 (immunoperoxidase; brown) followed by anti-CD5 (immunoalkaline phosphatase; blue). Blue CD5 positive B cells are indicated with arrowheads. They are present in the primary follicle in the fetus and the epithelium in the tonsil. Tumour cells in mantle cell lymphoma express CD5 with an intensity comparable to that seen in the fetal primary follicle and tonsillar epithelium. Note that the tonsillar mantle zone is unambiguously CD5 negative. W Su et al. J Clin Pathol 2000;53:395-397 Copyright © by the BMJ Publishing Group Ltd & Association of Clinical Pathologists. All rights reserved.