Pregabalin and pain after total knee arthroplasty: a double-blind, randomized, placebo- controlled, multidose trial† J.T. YaDeau, Y. Lin, D.J. Mayman,

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Pregabalin and pain after total knee arthroplasty: a double-blind, randomized, placebo- controlled, multidose trial† J.T. YaDeau, Y. Lin, D.J. Mayman, E.A. Goytizolo, M.M. Alexiades, D.E. Padgett, R.L. Kahn, K.M. Jules-Elysee, A.S. Ranawat, D.D. Bhagat, K.G. Fields, A.K. Goon, J. Curren, G.H. Westrich British Journal of Anaesthesia Volume 115, Issue 2, Pages 285-293 (August 2015) DOI: 10.1093/bja/aev217 Copyright © 2015 The Author(s) Terms and Conditions

Fig 1 Consolidated Standards of Reporting Trials diagram of patient flow through the study. POD, postoperative day. British Journal of Anaesthesia 2015 115, 285-293DOI: (10.1093/bja/aev217) Copyright © 2015 The Author(s) Terms and Conditions

Fig 2 Pain scores with flexion over time. Data are plotted as means with 95% confidence intervals. POD, postoperative day; NRS, Numeric Rating Scale pain score. British Journal of Anaesthesia 2015 115, 285-293DOI: (10.1093/bja/aev217) Copyright © 2015 The Author(s) Terms and Conditions

Fig 3 Opioid use over time. Data are plotted as means with 95% confidence intervals. POD, postoperative day. British Journal of Anaesthesia 2015 115, 285-293DOI: (10.1093/bja/aev217) Copyright © 2015 The Author(s) Terms and Conditions