Next-Generation Sequencing of the BRCA1 and BRCA2 Genes for the Genetic Diagnostics of Hereditary Breast and/or Ovarian Cancer Daniel Trujillano, Maximilian.

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Next-Generation Sequencing of the BRCA1 and BRCA2 Genes for the Genetic Diagnostics of Hereditary Breast and/or Ovarian Cancer Daniel Trujillano, Maximilian E.R. Weiss, Juliane Schneider, Julia Köster, Efstathios B. Papachristos, Viatcheslav Saviouk, Tetyana Zakharkina, Nahid Nahavandi, Lejla Kovacevic, Arndt Rolfs The Journal of Molecular Diagnostics Volume 17, Issue 2, Pages 162-170 (March 2015) DOI: 10.1016/j.jmoldx.2014.11.004 Copyright © 2015 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 Representation of the mean depth of coverage of BRCA1 (A) and BRCA2 (B) in the validation and discovery cohorts. Green lines represent the exons of the genes, red lines, the amplicons of the assay. The Journal of Molecular Diagnostics 2015 17, 162-170DOI: (10.1016/j.jmoldx.2014.11.004) Copyright © 2015 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions