Supplemental Figure S1. Expression of MYOCD, MYOCD ceRNA and miRNAs

Slides:

Advertisements

Similar presentations

Supplementary Figure 1. Caspase 8 expression and activation and Fas expression in NSCLC and normal lung cell lines. A Western blot analysis of DR4 and.

Advertisements

Supplemental Figure 1 A No. at risk T T T

Control siRNA BRG1 siRNA PTEN – Akt – p-Akt – p-GSK-3  – Cyclin D1 – BRG1 –  -actin – SW480 Supplemental data S1 Supplemental data S1. Effects of transduction.

Marker (%) Normal EPCs Mean ± SM (%) MMD EPCs Mean ± SM (%) CD ± ± 6.8 KDR27.3 ± ± 8.90 CD ± ± 3.93 CD ±

Supplemental Figure S1: Diagram to show previously reported interactions between EGFR and 23 other Egr1 target genes using Pathway Studio, Ariadne Inc.

Figure S1 A B Figure S1. SPATA2 is required for TNFα or zVAD.fmk induced necroptosis in L929 cells. (A) L929 cells were transfected with a pool of four.

Supplementary Figure S4

Fig. 4. miR-326, miR-330, and miR-3099 bound to the GFAP 3'-UTR and regulated GFAP expression. (A) Schematic diagram of potential binding sequence (seed.

From: Baicalein Inhibits Amadori-Glycated Albumin-Induced MCP-1 Expression in Retinal Ganglion Cells via a MicroRNA-124–Dependent Mechanism Invest. Ophthalmol.

Supplemental Digital Content 4

Finding the potential miRNA-binding sites of the selected SNPs

Effect of microRNA-135a on Cell Proliferation, Migration, Invasion, Apoptosis and Tumor Angiogenesis Through the IGF-1/PI3K/Akt Signaling Pathway in Non-Small.

A B C D Rao et al., 2012; Supplementary Figure S1 p = 0.03 p = NS

The Long Non-Coding RNA XIST Interacted with MiR-124 to Modulate Bladder Cancer Growth, Invasion and Migration by Targeting Androgen Receptor (AR) Cell.

Tsai-Der Chuang, Ph.D., Omid Khorram, M.D., Ph.D.

MiR-155-5p positively regulates colon cancer cell migration by targeting RhoA 2016 Molecular Biomarkers, Berlin | AMR AL-HAIDARI | Department of Clinical.

Volume 44, Issue 3, Pages (November 2011)

MiR-29 Regulates Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Michael Vanden Oever, Daniel Muldoon, Wendy Mathews, Ron McElmurry, Jakub.

Volume 16, Issue 3, Pages (March 2015)

Volume 8, Issue 1, Pages (July 2014)

MicroRNA-489 Plays an Anti-Metastatic Role in Human Hepatocellular Carcinoma by Targeting Matrix Metalloproteinase-7 Yixiong Lin, Jianjun Liu, Yuqi Huang,

A. D. B. C. - ΔNP63α - β-Actin IMEC - SUM MDA-MB IMEC

Supplemental Figure S1 a b

Volume 138, Issue 2, Pages (February 2010)

Cellular MicroRNA and P Bodies Modulate Host-HIV-1 Interactions

Nicastrin/miR-30a-3p/RAB31 Axis Regulates Keratinocyte Differentiation by Impairing EGFR Signaling in Familial Acne Inversa Yanyan He, Haoxiang Xu, Chengrang.

SP1 was a downstream target of miR-150-3p

Volume 147, Issue 2, Pages (October 2011)

Volume 19, Issue 10, Pages (October 2017)

A B C E F D IC50 = 567 nM IC50 = 83 nM HAP1 WT HAP1 TOPK

Molecular Therapy - Nucleic Acids

Supplemental Figure S4. Expression changes of phased and non-phased siRNAs among the three tissues examined The expression changes of phased and non-phased.

MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2 Ji-guang Zhang,

A B Supplementary figure S5 ** ** ** ** ** **

Posttranscriptional Crossregulation between Drosha and DGCR8

Fig. 5. GUCD1 was a direct target of miR-370 in HCC

mRNA level as % relative to

Bernard et al, Supplementary Figure S1

E7-less STING isoforms are proviral replication factors.

Kun-Peng Zhu, Xiao-Long Ma, Chun-Lin Zhang Molecular Therapy

N H N H Figure S1 parp-1 +/+ parp-1 -/- HIF-2 DAPI

Supplementary fig 1: Video showing heart function in zebrafish embryos targeted with morpholino oligonucleotides to reduce Brn-3a and Brn-3b compared with.

Jenny L. Weon, Seung Wook Yang, Patrick Ryan Potts Molecular Cell

Supplemental Figure 4 A no agonist MALP2 PAM3CSK4 GFP WT F217S

Volume 3, Issue 1, Pages (January 2013)

Knockdown efficiency of different shRNAs.

Cpeb knockdown mice. Cpeb knockdown mice. (A) Schematic representation of the transgene construct. The Zp3 promoter was inserted upstream of the Egfp open.

The lncRNA PDIA3P Interacts with miR-185-5p to Modulate Oral Squamous Cell Carcinoma Progression by Targeting Cyclin D2 Cheng-Cao Sun, Ling Zhang, Guang.

Knockdown of endogenous WT-hTER by a short hairpin RNA (siRNA) directed specifically against the human WT telomerase RNA template. Knockdown of endogenous.

Volume 24, Issue 10, Pages (October 2016)

CREB1 promotes the induction of endogenous ERα target genes.

Effect of the siRNA-mediated knockdown of endogenous MARCH8 on the expression levels of MARCH8 substrates, TfR and CD98, in HepG2 cells. Effect of the.

7 WT 6 irx1-6 ixr fold increased expression 3 2 n- 1 AT1G18710

MiRNA expression profiling in adipocytes from wild-type (WT) and leptin-deficient ob/ob mice. miRNA expression profiling in adipocytes from wild-type (WT)

MiR-431-5p directly targets RAF1 and is negatively correlated to RAF1 expression (A) The predicted binding sites of miR-431-5p and RAF1 3′-UTR, and mutant.

Molecular Therapy - Nucleic Acids

The Expression of MicroRNA-598 Inhibits Ovarian Cancer Cell Proliferation and Metastasis by Targeting URI Feng Xing, Shuo Wang, Jianhong Zhou Molecular.

BCL-3 regulates expression of stemness-associated Wnt targets.

GPR124 is the receptor for WNT7B responsible for synergistic signaling

Targeting eIF4E increases ZEB1 protein and mRNA levels and decreases ZEB1-targeting miR-200c and miR-141 microRNAs. Targeting eIF4E increases ZEB1 protein.

A, IGFBP-3 knockdown via siRNA using real-time qRT-PCR analysis.

Figure 4. MicroRNA (miR)-195 and miR-497 directly targets CD274

Induction of CDCP1 is regulated by Ras in NSCLC cells.

TFAP2A knockdown inhibits cell growth by targeting HIF-1α signaling.

Targeting DCLK1 by miRNA-137.

A Splicing-Independent Function of SF2/ASF in MicroRNA Processing

scrambled si-CLOCK scrambled si-CLOCK scrambled si-CLOCK scrambled

HOXA11-AS acts as a ceRNA for miR-1297.

A B C Name Sequence TIMP3 promoter

CREB1 binds at the proximal region of the TGFB2 promoter and induces its transcriptional activation. CREB1 binds at the proximal region of the TGFB2 promoter.

Presentation transcript:

Supplemental Figure S1. Expression of MYOCD, MYOCD ceRNA and miRNAs Supplemental Figure S1. Expression of MYOCD, MYOCD ceRNA and miRNAs. A, B: qRT-PCR analysis of the expression of MYOCD ceRNA and miRNAs in wild-type SMCs, Dicer-/- cells, IA and MMA tissues (control). C: MS2-RIP followed by qRT-PCR to identify endogenous miRNAs associated with the MYOCD and ceRNA 3’UTRs. D: RT-PCR analysis of MYOCD ceRNA expression in response to transfection of WT SMCs and DICER-/- cells with siRNA against MYOCD ceRNAs and selected non-targeting controls. E: Analysis of siRNA knockdown efficiency..