Appropriate vs. inappropriate antimicrobial therapy

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Presentation transcript:

Appropriate vs. inappropriate antimicrobial therapy P.G. Davey, C. Marwick Clinical Microbiology and Infection Volume 14, Pages 15-21 (April 2008) DOI: 10.1111/j.1469-0691.2008.01959.x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Inappropriate antimicrobial treatment and mortality rates with common bloodstream infection pathogens. Reproduced with permission from Ibrahim et al. [3]. CNS, coagulase-negative staphylococci; MRSA, methicillin-sensitive Staphylococcus aureus; MSSA, methicillin-sensitive S. aureus; VRE, vancomycin-resistant enterococci; E. coli, Escherichia coli; P. aeruginosa, Pseudomonas aeruginosa. Clinical Microbiology and Infection 2008 14, 15-21DOI: (10.1111/j.1469-0691.2008.01959.x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Classification and regression tree (CART) analysis of predictors of infection-related mortality in Staphylococcus aureus bacteraemia. Reproduced with permission from Lodise et al. [4]. APACHE II, acute physiology and chronic health evaluation; D-Tx, delayed treatment; E-Tx, early treatment; SAB, S. aureus bacteraemia. Clinical Microbiology and Infection 2008 14, 15-21DOI: (10.1111/j.1469-0691.2008.01959.x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Odds ratio of fatality related to inappropriate empiricaltreatment and other demographic, physiological and microbiological risk-factors [5]. Clinical Microbiology and Infection 2008 14, 15-21DOI: (10.1111/j.1469-0691.2008.01959.x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions