Volume 8, Issue 2, Pages (December 2001)

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Volume 8, Issue 2, Pages 105-111 (December 2001) Exposure to short-lasting impulse noise causes microglial and astroglial cell activation in the adult rat brain  Annette Säljö, Feng Bao, Anders Hamberger, Kenneth G. Haglid, Hans-Arne Hansson  Pathophysiology  Volume 8, Issue 2, Pages 105-111 (December 2001) DOI: 10.1016/S0928-4680(01)00067-0

Fig. 1 OX-42 immunoreactivity in the CA1 area of hippocampus. To the right of the letters in each figure, the regio superior of CA1 passes from the top downwards (arrow). Sham exposure (A). Exposure to 198 dB at 18 h (B) and 7 days (C). Exposure to 202 dB at 2 h (D), 18 h (E) and 7 days (F). Note the increased labeling of microglial cells in the exposed animals. Free floating method. Scale bar, 100 μm. Pathophysiology 2001 8, 105-111DOI: (10.1016/S0928-4680(01)00067-0)

Fig. 2 Morphometric analysis of the area occupied by microglia cell profiles (mean±S.E.M.) after exposure to 198 dB, (□) anterior hypothalamus; (○) posterior hypothalamus; (♢) lateral septal nucleus; and (▵) hippocampal CA 2–3 region. Control values=100%. Statistically significant changes are indicated by *. Pathophysiology 2001 8, 105-111DOI: (10.1016/S0928-4680(01)00067-0)

Fig. 3 GFAP immunoreactivity in cerebral cortex. Sham exposure (A), the immunoreactivity is localized to slender astrocytes. Exposure to 198 dB at 2 (B) and at 21 days (C). Exposure to 202 dB at 18 h (D), 2 days (E) and 21 days (F). Note the hypertrophy of immunostained astrocytes. Free floating method. Scale bar, 100 μm. Pathophysiology 2001 8, 105-111DOI: (10.1016/S0928-4680(01)00067-0)

Fig. 4 GFAP immunoreactivity in the CA1 area of hippocampus. Sham exposure (A). A dense network of immunoreactive astrocytes is seen at 21 days after exposure to 202 dB (B). Free floating method. Scale bar, 100 μm. Pathophysiology 2001 8, 105-111DOI: (10.1016/S0928-4680(01)00067-0)