Nonlinear Relationship Between Body Mass Index and Esophageal Acid Exposure in the Extraesophageal Manifestations of Reflux Muhammad Aslam, James C.

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Presentation transcript:

Nonlinear Relationship Between Body Mass Index and Esophageal Acid Exposure in the Extraesophageal Manifestations of Reflux Muhammad Aslam, James C. Slaughter, Marion Goutte, C. Gaelyn Garrett, David Hagaman, Michael F. Vaezi Clinical Gastroenterology and Hepatology Volume 10, Issue 8, Pages 874-878 (August 2012) DOI: 10.1016/j.cgh.2011.12.032 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 Graphic representation of multivariable linear regression model controlling for esophagitis status, presence of hiatal hernia, age, and sex in patients with extraesophageal symptoms. There is an S-shaped relationship between increasing BMI and the percentage of time the pH was less than 4. The largest increase in acid exposure occurred between a BMI of 25 to 30 independent of esophagitis. Clinical Gastroenterology and Hepatology 2012 10, 874-878DOI: (10.1016/j.cgh.2011.12.032) Copyright © 2012 AGA Institute Terms and Conditions