C.G. Giske, C. Borén, B. Wretlind, G. Kronvall

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Meropenem susceptibility breakpoint for Pseudomonas aeruginosa strains hyperproducing mexB mRNA C.G. Giske, C. Borén, B. Wretlind, G. Kronvall Clinical Microbiology and Infection Volume 11, Issue 8, Pages 662-669 (August 2005) DOI: 10.1111/j.1469-0691.2005.01182.x Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Zone diameter histogram for Pseudomonas aeruginosa and meropenem (Karolinska University Hospital 2003; n = 1572 isolates). Dashed lines indicate breakpoints between the susceptibility categories. R, resistant; I, intermediate; S, sensitive. Clinical Microbiology and Infection 2005 11, 662-669DOI: (10.1111/j.1469-0691.2005.01182.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Scatterplot showing the correlation between zone diameters for meropenem (MER) and imipenem (IMI) in clinical isolates of Pseudomonas aeruginosa from Karolinska University Hospital 2003 (n = 1572 isolates). Dashed lines indicate breakpoints between the susceptibility categories. R, resistant; I, intermediate; S, sensitive. Clinical Microbiology and Infection 2005 11, 662-669DOI: (10.1111/j.1469-0691.2005.01182.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Normalised resistance interpretation performed on zone diameter histogram for Pseudomonas aeruginosa and meropenem from Karolinska University Hospital 2003 (n = 1572 isolates). The dashed line indicates the suggested susceptibility breakpoint, i.e., 2.5 × SD, from the mean of the distribution of the reconstructed susceptible population. Clinical Microbiology and Infection 2005 11, 662-669DOI: (10.1111/j.1469-0691.2005.01182.x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions