Cell to Cell Communication via Ion-Channel Linked Receptors

Slides:

Advertisements

Similar presentations

SYNAPSES AND DRUGS.

Advertisements

NERVE IMPULSE TRANSMISSION

Gated Ion Channels Ahu Karademir Andrei Vasiliev.

بسم اللة الرحمن الرحيم Muscle and neuron as excitable tissue.

1 © Patrick An Introduction to Medicinal Chemistry 3/e Chapter 6 PROTEINS AS DRUG TARGETS: RECEPTOR STRUCTURE & SIGNAL TRANSDUCTION Part 1: Sections 6.1.

Synaptic Signaling & The Action Potential

Questions 17-1 Q: What happens to a nerve impulse once it reaches the end of an axon? Q: How does one neuron communicate with another?

NERVOUS TISSUE Chapter 44. What Cells Are Unique to the Nervous System? Nervous systems have two categories of cells: Neurons generate and propagate electrical.

The Nervous System (II) Rachel Cohen, Grace Huddleston, Artemis Metaxa, Elisa Rocha.

MARION COPELAND AND LYNNETTE LACEK FIRST YEAR MEDICAL STUDENTS PENN STATE HERSHEY COLLEGE OF MEDICINE The Action Potential and Neurotransmission.

Membrane Transport1 Not responsible for: Nernst Equation, other than to know what it’s used for. Chapter 12 Membrane Transport Questions in this chapter.

Sci2 Lect 5 Synaptic Transmission ©Dr Bill Phillips 2002, Dept of Physiology Fast Excitatory Postsynaptic Potentials Ligand gated ion channels Presynaptic.

The Action Potential And the synaptic junction Joy Killough Round Rock ISD.

Neurophysiology II: The Synapse Synapse Defined Space between adjacent neurons! Relays information from one neuron to another! Neuron  Neuron Neuron.

AP Biology Nervous Systems Part 3.  I. Synapses – These are the gaps between neurons or between neuron and effector cells.  A. There are two types of.

Action potential 1. Action potentials arriving at the presynaptic terminal cause voltage- gated Ca2+ channels to open. Ca Presynaptic terminal.

Principles of Bioelectricity. Key Concepts The cell membrane is composed of a phospholipid bilayer The cell membrane may have transport channels (made.

Do Now Complete Part 1 on your worksheets with a partner. A problem for you to solve: – Given that you know the axon sends signals electrically, and that.

Afferent Nerves Efferent Nerves cell body: cell body: central part of cell; contains the nucleus axon: axon: long slender extension from cell body; used.

 Chapter 48 Gaby Gonzalez Joyce Kim Stephanie Kim.

The Synapse and Synaptic Transmission

Nerve Impulses and Reflex Arcs

Chemical synapses: post-synaptic mechanisms

Building the Model Neurons or parts of neurons Ions Gates dendrite

Neurons, Synapses and Signaling

NERVE CELLS by Grace Minter.

Human Anatomy / Physiology

Synaptic Transmission

Structure of a Neuron: At the dendrite the incoming

Animal Cell Chromatin.

Nervous System Chapter 48.

THE NERVE IMPULSE.

Neurons, Signals, Synapses

Cell Communication.

An Introduction to Medicinal Chemistry 3/e PROTEINS AS DRUG TARGETS:

Synaptic Signaling & The Action Potential

Neuron Function.

Nerve Impulses.

AP Biology Nervous Systems Part 3.

Animal Cell Chromatin.

Chapter 49 Table of Contents Section 1 Neurons and Nerve Impulses.

1. An action potential arrives at the

SYNAPSES AND DRUGS.

ION CHANNELS AS DRUG TARGETS &

Neuron Physiology.

Interneuronal connections

SYNAPSES AND DRUGS.

Electrical Current and the Body

Effects of Excitatory and Inhibitory Potentials on Action Potentials

1. An action potential arrives at the

A junction that mediates information transfer from one neuron:

Electrochemical Gradient Causing an Action Potential

Gnarly Nervous Physiology

SYNAPSES AND DRUGS.

Neurotransmission Across a Synapse

Review: Cell Communication

Module 1 Communication and homeostasis

An Introduction to Medicinal Chemistry 3/e PROTEINS AS DRUG TARGETS:

Gates + Potentials.

Animal Cell Cell Membrane.

Volume 15, Issue 5, Pages R154-R158 (March 2005)

Synaptic Transmission and Integration

Do Now: 1. What is 1 of the characteristics of nerve signals that you defined from the “dominos” lab? 2. What is the role of the axon? 3. What creates.

Neurophysiology NEUROTRANSMISSION

Do Now: 1. What is 1 of the characteristics of nerve signals that you defined from the “dominos” lab? 2. What is the role of the axon? 3. What creates.

THE NERVOUS SYSTEM II pp

Cell to cell communication in the nervous system

Presentation transcript:

Cell to Cell Communication via Ion-Channel Linked Receptors Thursday, January 17, 2019 Cell to Cell Communication via Ion-Channel Linked Receptors Packet #18 Chapter #11

Ion-Channel-Linked Receptors Thursday, January 17, 2019Thursday, January 17, 2019 Also known as transmitter-gated ion channels Found in muscle and nervous tissue Convert chemical signals into electrical signals Receptors serve for rapid transmission across synapses in the nervous system Chemical signal arrives as a neurotransmitter Delivered to the outside of the target cell Chemical signal changes to an electrical signal in the form of a change in voltage across the plasma membrane

Ion-Channel-Linked Receptors II Thursday, January 17, 2019Thursday, January 17, 2019 Neurotransmitter binds Receptor alters its conformation Causes channel to open (or close) Allows the flow of specific ions across membrane Na+ K+ Ca2+ Cl- Driven by electrochemical gradient, ions rush in or out of the cell Depends on the concentration gradient Results in a change in the membrane potential of the post-synaptic cell Change promotes, or inhibits, neurotransmission

Ion-Channel-Linked Receptors III Thursday, January 17, 2019Thursday, January 17, 2019 Examples of Neurotransmitters Nicotinic acetylcholine Nerve and muscle GABA Γ-aminobutyric acid CNS Glycine Special Note Many ion channels are not directly coupled to their receptors but are coupled by G-proteins

Ion Channel Receptors Thursday, January 17, 2019Thursday, January 17, 2019