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Double-Blind, Placebo-Controlled, Randomized Trial of Octreotide in Malignant Bowel Obstruction David C. Currow, FRACP, Stephen Quinn, PhD, Meera Agar, FRACP, Belinda Fazekas, GradDipCommHealth, Janet Hardy, FRACP, Nikki McCaffrey, MSc, Simon Eckermann, PhD, Amy P. Abernethy, MD, Katherine Clark, FRACP Journal of Pain and Symptom Management Volume 49, Issue 5, Pages 814-821 (May 2015) DOI: 10.1016/j.jpainsymman.2014.09.013 Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 1 CONSORT participant flow diagram. Journal of Pain and Symptom Management 2015 49, 814-821DOI: (10.1016/j.jpainsymman.2014.09.013) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 2 Number of days free of vomiting between groups. P-value for difference in medians from the Mann-Whitney U test. *Any people in these columns had vomiting on each of the three days of the study. **Any people in these columns had no vomiting during the study. Journal of Pain and Symptom Management 2015 49, 814-821DOI: (10.1016/j.jpainsymman.2014.09.013) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 3 Mean unadjusted number of vomiting episodes between baseline and Day 1. P-value for difference between groups and error bars are 95% CI. Journal of Pain and Symptom Management 2015 49, 814-821DOI: (10.1016/j.jpainsymman.2014.09.013) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions