Clearance of Meperidine and Its Metabolite Normeperidine in Hemodialysis Patients With Chronic Noncancer Pain Che-Hao Hsu, MD, Tso-Chou Lin, MD, Chih-Cherng.

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Presentation transcript:

Clearance of Meperidine and Its Metabolite Normeperidine in Hemodialysis Patients With Chronic Noncancer Pain Che-Hao Hsu, MD, Tso-Chou Lin, MD, Chih-Cherng Lu, MD, PhD, Shih-Hua Lin, MD, Shung-Tai Ho, MD, MS Journal of Pain and Symptom Management Volume 47, Issue 4, Pages 801-805 (April 2014) DOI: 10.1016/j.jpainsymman.2013.05.007 Copyright © 2014 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Equations of plasma reduction and extraction ratios as well as the clearance rates of meperidine and normeperidine by hemodialysis. Journal of Pain and Symptom Management 2014 47, 801-805DOI: (10.1016/j.jpainsymman.2013.05.007) Copyright © 2014 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Mean plasma concentrations of meperidine and normeperidine during four-hour hemodialysis. Journal of Pain and Symptom Management 2014 47, 801-805DOI: (10.1016/j.jpainsymman.2013.05.007) Copyright © 2014 U.S. Cancer Pain Relief Committee Terms and Conditions