Xinmei Zhang, M. D. , Bangchun Lu, M. D. , Xiufeng Huang, M. D

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Innervation of endometrium and myometrium in women with painful adenomyosis and uterine fibroids  Xinmei Zhang, M.D., Bangchun Lu, M.D., Xiufeng Huang, M.D., Hong Xu, M.D., Caiyun Zhou, M.D., Jun Lin, M.D.  Fertility and Sterility  Volume 94, Issue 2, Pages 730-737 (July 2010) DOI: 10.1016/j.fertnstert.2009.03.026 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 PGP9.5 and NF-immunoreactive nerve fibers in the functional and basal layers of the endometrium and in the myometrium in women with uterine fibroids and adenomyosis. (A) Endometrium from the functional layer of a pain woman with uterine fibroids stained for PGP9.5 (original magnification ×400). Arrows denote multiple small nerve fibers in the functional layer. (B) Endometrium from the functional layer of a nonpain woman with adenomyosis stained for PGP9.5 (original magnification ×400). No nerve fibers could be identified. (C) Myometrial–endometrial interface from a pain woman with adenomyosis stained for PGP9.5 (original magnification ×200). Some large nerve fibers could be identified. (D) Myometrial–endometrial interface from a nonpain woman with adenomyosis stained with PGP9.5 (original magnification ×200). There were some small nerve fibers in the basal layer. (E) Myometrium from a pain woman with adenomyosis stained for PGP9.5 (original magnification ×400). More large nerve fibers could be identified. (F) Myometrial–endometrial interface from a pain woman with adenomyosis stained for NF (original magnification ×400). Several nerve fibers could be identified. Scale bars represent 30 μm in (A), (B), and (E); 50 μm in (C), (D) and (F). Fertility and Sterility 2010 94, 730-737DOI: (10.1016/j.fertnstert.2009.03.026) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions