Comparison of the P-value significance between Wild Type and ΔGLN3

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Comparison of the P-value significance between Wild Type and ΔGLN3 ANOVA WT ΔGLN3 p < 0.05 38.42% 30.11% p < 0.01 24.67% 16.29% p < 0.001 13.90% 6.53% p < 0.0001 7.43% 2.04% B-H p < 0.05 26.76% Bonferroni p < 0.05 3.68% 0.42%

ΔGLN3 STEM Significance Profiles

ΔGLN3 Profile 45

ΔGLN3 Profile 9

ΔGLN3Profile 2

ΔGLN3Profile 22

ΔGLN3Profile 48

ΔGLN3Profile 31

Wild Type Clusters

Wild Type Profile 45

Wild Type Profile 22

Wild Type Profile 9

Wild Type Profile 28

Wild Type Profile 48

Wild Type Profile 0

ΔGLN3: Binding AND Expression

ΔGLN3: Binding PLUS Expression

ΔGLN3: Only DNA Binding

ΔGLN3: GRNsight Binding AND Expression

ΔGLN3: GRNsight Binding PLUS Expression

ΔGLN3: GRNsight Only DNA Binding

Wild Type: Binding PLUS Expression

Wild Type: DNA Binding Only

Wild Type: DNA Binding PLUS Expression

Wild Type: GRNSight Binding PLUS Expression

Wild Type: DNA Binding Only

Wild Type: DNA Binding AND Expression