The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification.

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The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors Kazuya Kondo, MD, Paul Van Schil, MD, Frank C Detterbeck, MD, Meinoshin Okumura, MD, Kelly Stratton, MS, Dorothy Giroux, MS, Hisao Asamura, MD, John Crowley, PhD, Conrad Falkson, MBChB, Pier Luigi Filosso, MD, Giuseppe Giaccone, MD, James Huang, MD, Jhingook Kim, MD, Marco Lucchi, MD, Mirella Marino, MD, Edith M Marom, MD, Andrew G. Nicholson, MD, Enrico Ruffini, MD Journal of Thoracic Oncology Volume 9, Issue 9, Pages S81-S87 (September 2014) DOI: 10.1097/JTO.0000000000000291 Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Evaluable patients for the N and M component analysis. Diagram of evaluable patients available for analysis, by N and M characteristic, with the proportion contributed by the Japanese Association for Research in the Thymus (JART). Journal of Thoracic Oncology 2014 9, S81-S87DOI: (10.1097/JTO.0000000000000291) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 ITMIG/IASLC Lymph Node Map. Anterior and deep node regions as depicted on axial images. Anterior region (blue); deep region (purple). For further detail see Bhora et al.5 (A) Thoracic inlet; (B) paraaortic level; (C) AP window level; (D) carina level. AA, ascending aorta; Az, azygos vein; CCA, common carotid artery; BR, bronchus; Clav, clavicle; DA, descending aorta; E, esophagus, IJV, internal jugular vein; LB, left main bronchus; LPA, left pulmonary artery; LSPV, left superior pulmonary vein; PT, pulmonary trunk; RB, right main bronchus; RPA, right pulmonary artery; SVC, superior vena cava; Tr, trachea. Journal of Thoracic Oncology 2014 9, S81-S87DOI: (10.1097/JTO.0000000000000291) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Outcomes of all patients by proposed N and M categories. Outcomes of all patients with a thymic malignancy of any type. A, Cumulative incidence of recurrence, R0 resected patients; (B) overall survival, R0 resected patients; (C) overall survival, all patients (any R status); point estimates at 5 and 10 years are provided in the tables. There are no statistically significant differences between the curves. CI, 95% confidence interval; Cum. Inc. of Recurrence, cumulative incidence of recurrence; N, total number of evaluable patients; OS, overall survival; R0, complete resection; Yr, year. Journal of Thoracic Oncology 2014 9, S81-S87DOI: (10.1097/JTO.0000000000000291) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions