Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up Hamed Esfandiari, MD,

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Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up Hamed Esfandiari, MD, Mohammad Pakravan, MD, Shahin Yazdani, MD, Azadeh Doozandeh, MD, Mehdi Yaseri, PhD, Ian P. Conner, MD, PhD Ophthalmology Glaucoma Volume 1, Issue 1, Pages 66-74 (July 2018) DOI: 10.1016/j.ogla.2018.06.003 Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 1 Diagram showing study design and patient retention. BRVO = branch retinal vein occlusion; TI = intra-Tenon mitomycin C injection; TS = subconjunctival application of mitomycin C-soaked sponges. Ophthalmology Glaucoma 2018 1, 66-74DOI: (10.1016/j.ogla.2018.06.003) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 2 Kaplan-Meier plots showing (A) the cumulative probability of success in all patients and (B) with each method defining inadequate intraocular pressure (IOP) reduction as IOP of more than 21 mmHg or less than 20% reduction below the baseline. These criteria must have been present on 2 consecutive visits after 3 months to qualify as failure. TI = intra-Tenon mitomycin C injection; TS = subconjunctival application of mitomycin C-soaked sponges. Ophthalmology Glaucoma 2018 1, 66-74DOI: (10.1016/j.ogla.2018.06.003) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 3 Graph showing intraocular pressure (IOP) at baseline and follow-up. Data mean ± standard error. SD = standard deviation; TI = intra-Tenon mitomycin C injection; TS = subconjunctival application of mitomycin C-soaked sponges. Ophthalmology Glaucoma 2018 1, 66-74DOI: (10.1016/j.ogla.2018.06.003) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 4 Graphs showing Bleb morphologic parameters during follow-up. IBAGS = Indiana Bleb Appearance Grading Scale; SD = standard deviation; TI = intra-Tenon mitomycin C injection; TS = subconjunctival application of mitomycin C-soaked sponges. Ophthalmology Glaucoma 2018 1, 66-74DOI: (10.1016/j.ogla.2018.06.003) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions