Mirnela Byku, and Douglas L. Mann BTS 2016;1:95-106 Primary Clinical Endpoint of the ANTHEM-HF Trial Mean and 95% confidence intervals of echocardiographic changes after 6 months of autonomic regulation therapy (overall, left-side treatment, and right-side treatment). Reproduced with permission from Premchand RK et al. (23). ANTHEM-HF = Autonomic Regulation Therapy via Left or Right Cervical Vagus Nerve Stimulation in Patients With Chronic Heart Failure; LVEF = left ventricular ejection fraction; LVESV = left ventricular end-systolic volume; LVESD = left ventricular end-systolic diameter. Mirnela Byku, and Douglas L. Mann BTS 2016;1:95-106 The Authors